International Journal of Clinical Case Reports 2018, Vol.8, No.2, 5-9
5
Research Report Open Access
Systemic Lupus Erythematosus: A Case Report
S.L. Chavan
, Yash Merchant, R.S. Deshmukh
Bharati Vidyapeeth Dental College and Hospital, Pune, Maharashtra, India
Corresponding author email
International Journal of Clinical Case Reports 2018, Vol.8, No.2 doi
Received: 24 Jan., 2018
Accepted: 22 Feb., 2018
Published: 23 Mar., 2018
Copyright © 2018
Chavan et al., This is an open access article published under the terms of the Creative Commons Attribution License, which permits
unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:
Chavan S.L., Merchant Y., and Deshmukh R.S., 2018, Systemic lupus erythematosus: a case report, International Journal of Clinical Case Reports, 8(2):
5-9 (doi
Abstract
Systemic lupus erythematosus is an immunologically mediated condition. It is also called as connective tissue disease.
With more than 1.5 million people affected, it may exhibit any one of several clinicopathological forms. This condition is
characterized by the presence of abnormal antibodies and immune complex. SLE has a wide range of symptoms like joint pain, skin
rash, fever, and can affect the kidneys, lungs and nervous system. Symptoms have remission and exacerbation. Lupus is a Latin word
for ―wolf‖ and erythematosus is from the Greek word for ―red‖ and refers to the color of the rash.
Keywords
Lupus erythematosus; Autoimmune disease; Collagen disorder
Background
Lupus erythematosus (L.E) is a chronic autoimmune disease in which auto-antibodies bind to components of the
cell surface, cytoplasm and nucleus, including nucleic acids and nucleoprotein particles. This antibody binding
prompts an inflammatory reaction, which leads to cell and tissue destruction (Louis and Fernandes, 2001).
L.E occurs most commonly in young women and ranges from mild cutaneous lesions and ⁄ or arthritis to renal
failure or intense nervous, cardiac and hematological disturbances (Neville et al., 2009).
L.E can manifest as different clinical forms: systemic lupus erythematosus (SLE), chronic cutaneous lupus
erythematosus and subacute cutaneous lupus erythematosus (Burge et al., 1989).
A wide spectrum of oral mucosal lesions is found in cutaneous and systemic forms of LE: cheilitis, erythematous
patches, ‗honeycomb‘ plaques, discoid lesions, lichen planus (LP)-like lesions and discrete ulcers have been
described. In established disease, reported prevalence rates range from 9% to 45% of cases (Jonsson et al., 1984;
Rowell and Goodfield, 1998) although the true figure may be nearer to 20% (Lever et al., 1983).
1 Case Report
A 33 year old female patient came to the department of Oral Patholgoy and Microbiology, Bharati Vidyapeeth
Dental College, with the chief complaint of ulcers and burning sensation in the oral cavity since last 6 months.
She also complained of pain in the joints of the lower limbs. Extra oral examination and facial appearance
appeared normal (Figure 1).
Figure 1 Frontal view
