Computational Molecular Biology 2016, Vol.6, No.4, 1-12
10
Acknowledgements
BP was supported by the College of Graduate Studies, Youngstown State University (YSU), VA and JM were
supported by the Center for Applied Chemical Biology, YSU. The work is also supported by a Research
Professorship to XM by YSU.
Table 3 Comparison of protein families in secretomes of three protist species having different lifestyles
PFam ID
D. discoideum P. infestans T. cruzi
PFam
Description
pfam11912
52
0
0
DUF3430
Protein of unknown function (DUF3430)
pfam09478
44
0
0
CBM49
Carbohydrate binding domain CBM49
pfam00112
16
8
23
Peptidase_C1
Papain family cysteine protease
pfam03265
9
1
0
DNase_II
Deoxyribonuclease II
pfam02221
8
0
0
E1_DerP2_DerF2 ML domain
pfam07691
8
2
0
PA14
PA14 domain
pfam04562
7
0
0
Dicty_spore_N
Dictyostelium spore coat protein
pfam04916
7
0
0
Phospholip_B
Phospholipase B
pfam10500
7
0
0
SR-25
Nuclear RNA-splicing-associated protein
pfam00144
6
0
0
Beta-lactamase
Beta-lactamase
pfam00383
6
0
2
dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase
pfam00759
6
0
0
Glyco_hydro_9
Glycosyl hydrolase family 9
pfam05577
6
1
5
Peptidase_S28
Serine carboxypeptidase S28
pfam09286
6
0
0
Pro-kuma_activ
Pro-kumamolisin
pfam00964
0
39
0
Elicitin
Elicitin
pfam16810
0
36
0
RXLR
RXLR phytopathogen effector protein
pfam05630
0
24
0
NPP1
Necrosis inducing protein (NPP1)
pfam09461
0
22
0
PcF
Phytotoxin PcF protein
pfam00089
0
17
0
Trypsin
Trypsin
pfam00188
3
14
0
CAP
Cysteine-rich secretory protein family
pfam00295
0
14
0
Glyco_hydro_28
Glycosyl hydrolases family 28
pfam03211
0
14
0
Pectate_lyase
Pectate lyase
pfam05642
0
12
1
Sporozoite_P67
Sporozoite P67 surface antigen
pfam13091
1
10
0
PLDc_2
PLD-like domain
pfam00588
0
8
1
SpoU_methylase
SpoU rRNA Methylase family
pfam16656
3
7
0
Pur_ac_phosph_N Purple acid Phosphatase
pfam00050
0
7
0
Kazal_1
Kazal-type serine protease inhibitor domain
pfam00264
0
7
0
Tyrosinase
Common central domain of tyrosinase
pfam02055
0
7
0
Glyco_hydro_30
O-Glycosyl hydrolase family 30
pfam03639
0
7
0
Glyco_hydro_81
Glycosyl hydrolase family 81
pfam01565
3
6
0
FAD_binding_4
FAD binding domain
pfam04147
1
6
45
Nop14
Nop14-like family
pfam00194
0
6
0
Carb_anhydrase
Eukaryotic-type carbonic anhydrase
pfam01083
0
6
0
Cutinase
Cutinase
pfam01095
0
6
0
Pectinesterase
Pectinesterase
pfam01670
0
6
0
Glyco_hydro_12
Glycosyl hydrolase family 12
pfam01456
0
0
345
Mucin
Mucin-like glycoprotein
pfam13859
0
0
198
BNR_3
BNR repeat-like domain
pfam01457
1
0
102
Peptidase_M8
Leishmanolysin
pfam12517
0
0
90
DUF3720
Protein of unknown function (DUF3720)
pfam05086
0
0
57
Dicty_REP
Dictyostelium (Slime Mold) REP protein
pfam12446
0
0
50
DUF3682
Protein of unknown function (DUF3682)
pfam01762
0
1
41
Galactosyl_T
Galactosyltransferase
pfam01299
4
0
21
Lamp
Lysosome-associated membrane glycoprotein
pfam00183
1
0
18
HSP90
Hsp90 protein
