IJMMS_2025v15n4

International Journal of Molecular Medical Science, 2025, Vol.15, No.4, 195-204 http://medscipublisher.com/index.php/ijmms 199 targeted approach can rapidly improve poor blood coagulation, reduce unnecessary blood transfusions, and prevent the "three fatal problems" (coagulation dysfunction, hypothermia and acidosis) from worsening - if these problems are not addressed early, the patient's risk of death will increase (Mitra et al., 2012; Philips et al., 2017; Maegele, 2018; Schmulevich et al., 2024). 5.2 Empirical research: improving the prognosis of trauma patients through nursing intervention Actual research shows that nursing intervention has a positive impact on the outcome of trauma treatment. The implementation of early coagulation support programs, including timely use of tranocyclic acid, fibrinogen and blood products, has been proven to reduce the use of blood products in patients with severe trauma, shorten hospital stays, and improve hemostasis effects (Bocci et al., 2019). Nursing staff are the key force in implementing these programs. They can ensure timely intervention and continuous monitoring, which is related to the better recovery of patients. In addition, the multidisciplinary team collaboration model composed of nurses, pharmacists and emergency personnel has also been proven that as long as early detection and intervention methods are adopted, the survival rate of patients can be improved. The use of a unified blood transfusion protocol and the rapid response to bleeding situations are usually coordinated and advanced by the nursing team, which also reflects the important role of nursing in optimizing trauma care and reducing preventable deaths (Phillips et al., 2017). 5.3 Trends in individualized care and precise intervention In the field of trauma care, there is an increasing tendency to provide personalized and precise intervention services for patients. Under the guidance of real-time viscoelastic tests (such as TEG, ROTEM), targeted coagulation therapy enables medical staff to formulate usage plans for blood products and hemostatic drugs based on the unique coagulation conditions of each patient (Maegele, 2018; Maegele, 2019). This method can reduce the need for blood transfusion, improve the hemostasis effect, and may also lower the risk of disease. Emerging technologies such as machine learning algorithms and clinical decision support systems are being combined to better identify high-risk patients at an early stage and select the right time for intervention. These precise methods, coupled with the continuous research on new diagnostic and therapeutic approaches, represent the future development direction of trauma care. The ultimate goal is to further increase the survival probability of patients and the recovery effect of physical function through personalized and data-supported intervention measures (Asehnoune et al., 2017; Maegele, 2019; Schmulevich et al., 2024). 6 Current Research Hotspots and Controversies 6.1 The synergistic mechanism of hemostasis care and coagulation monitoring Hemostasis care and coagulation monitoring work in tandem to help trauma patients recover better by quickly identifying coagulation problems and guiding targeted intervention measures. Combining real-time viscoelastic tests (such as TEG and ROTEM) with personalized hemostasis treatment enables doctors and nurses to formulate blood product usage and medication regimen based on the constantly changing needs of patients, reduce unnecessary blood transfuses, and increase the survival probability of patients (Phillips et al., 2017; Maegele, 2018; Maegele, 2019; Gratz et al., 2020). This dynamic feedback approach can ensure that hemostasis intervention is both timely and effective. 6.2 Optimization of the nursing pathway for patients with traumatic massive hemorrhage To optimize the nursing process for patients with traumatic massive hemorrhage, it is necessary to incorporate a unified plan that includes early identification of the condition, rapid response, and multidisciplinary collaboration. Nurses are the core personnel in performing injury control resuscitation, initiating massive blood transfusion protocols, and ensuring the timely supply of blood products and hemostatic drugs (Phillips et al., 2017; Karl et al., 2021). In a trauma treatment team, simplifying communication procedures and clarifying each person's job responsibilities can enhance work efficiency, reduce delays, and provide support for scientific intervention measures that are crucial for patients' survival (Karl et al., 2021; Zhu et al., 2025).

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