Cancer Genetics and Epigenetics, 2025, Vol.13, No.6, 254-264 http://medscipublisher.com/index.php/cge 259 5 Key Factors Influencing the Therapeutic Effect of Multidisciplinary Teams 5.1 Team collaboration and organizational management Good teamwork is the foundation for multidisciplinary teams (MDTS) to achieve good results in cancer treatment. A smoothly running MDT usually has a leader with clear responsibilities, members respect each other, and there are not many obstacles for people from different specialties to communicate. Team leaders play a very crucial role in creating a harmonious and trusting working atmosphere, ensuring that everyone has the opportunity to speak, and promoting unified decisions made by all. On the contrary, if there is a strong sense of hierarchy within the team, a lack of mutual trust, or unclear division of labor and responsibilities, it will undermine collaboration, cause decision-making delays, and may also affect the treatment outcome of patients (Horlait et al., 2021; Shin et al., 2025). Therefore, it is recommended to conduct communication skills and leadership training regularly to help improve the overall teamwork level and enable each member to have a stronger coping ability when facing complex cases (Alfieri et al., 2023; Li, 2025). Organizational management is also crucial for the effective operation of MDT. Reasonably arranging meeting time, leaving sufficient preparation time, and controlling the number of cases discussed each time are all keys to ensuring the quality of discussions and promptly determining treatment plans. Research shows that if the schedule is too full, the tasks are too heavy, or people's enthusiasm for participation is not high, it will affect the quality of decision-making and reduce the level of care. Institutions that attach great importance to team management, optimize meeting arrangements, and constantly monitor team performance are more capable of maintaining high-quality MDT work, thereby achieving better treatment outcomes for patients (Rosell et al., 2018; Soukup et al., 2018; Luu, 2021). 5.2 Information sharing and clinical decision support system Efficient information transmission is an important prerequisite for MDT to make reasonable and reliable decisions. Complete medical information - such as imaging examination results, pathological reports and the patient's thoughts - helps to take all relevant circumstances into account during the discussion (Rosell et al., 2018; Soukup et al., 2018). However, in actual work, there are still situations such as incomplete information, late issuance of pathological reports, and insufficient participation of non-doctor members like nurses, which affect the quality of judgment. To improve these issues, it is necessary to establish a unified and clear data collection process and encourage all types of healthcare workers, including nurses, to actively participate in discussions (Horlait et al., 2022). The application of digital tools and clinical decision support systems (CDSS) has made information sharing and daily processes smoother. CDSS can automatically summarize and organize patient data from different sources, making pre-meeting preparations more time-saving and labor-saving. It can also provide reference opinions based on existing treatment guidelines, reducing the workload and helping the team form treatment plans more quickly and accurately. Whether such systems can function effectively depends on whether they can be well integrated with electronic medical records, whether the content is updated in a timely manner, and whether medical staff have received adequate training. When CDSS is effectively combined with digital platforms, both the operational efficiency of MDT and the quality of diagnosis and treatment for patients can be significantly improved (Soo et al., 2021; Hendriks et al., 2024). 5.3 Institutional support and resource allocation The support from institutions such as hospitals is an important guarantee for the effective operation of MDT. Only by rationally allocating human resources and other resources, such as dedicated coordinators, administrative assistance and medical equipment, can MDT carry out its work smoothly (Rosell et al., 2018). Hospitals should allow team members sufficient time to prepare and attend meetings, and also provide continuous training and career development opportunities. If resources are insufficient, MDT may encounter problems such as too many cases, tight schedules, and inability to arrange them all, ultimately affecting the quality of patient care (Soukup et al., 2018; Luu, 2021).
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