Cancer Genetics and Epigenetics, 2025, Vol.13, No.6, 254-264 http://medscipublisher.com/index.php/cge 258 anxiety and depression, and reduced discomfort during surgery (Taberna et al., 2020; Xie et al., 2024). For patients with advanced cancer, the combination of MDT and palliative care can significantly reduce negative emotions and increase the level of social support they feel, thereby further improving the overall quality of life (Liu et al., 2023; Wang, 2025). Figure 1 Disease-free survival and overall survival in high or general multidisciplinary team quality (Adopted from Ma et al., 2024) The comprehensive care approach of MDT not only focuses on the physical pain of patients, but also attaches importance to their emotional and social needs (Taberna et al., 2020; Liu et al., 2023). By incorporating supportive medical staff such as psychological experts, social workers, and palliative care experts, MDT can provide comprehensive assistance throughout the entire process of patients fighting cancer. This multi-faceted care model can make patients more motivated, promote doctors and patients to jointly determine the treatment plan, and help patients better cope with the stress during the cancer treatment process (Biseglia et al., 2024; Xie et al., 2024). 4.3 Improve treatment compliance and patient satisfaction The degree of patient participation in multidisciplinary team (MDT) treatment is also closely related to whether they are willing to cooperate with the treatment and whether they are satisfied with it. Patients under MDT management are more likely to complete all treatments on time and as planned, seek medical attention promptly, and receive relatively adequate support throughout the process (Prades et al., 2015). A survey of colorectal cancer patients found that 93.5% of them were satisfied with MDT care, and 89.5% believed that they had received sufficient attention during treatment. Meanwhile, MDT can also reduce the time patients wait for examination and start treatment, thereby further improving patient satisfaction (Lucarini et al., 2022; Mangone et al., 2024). The MDT cooperation model enables smoother communication between doctors and patients, more unified nursing arrangements, and allows doctors and patients to make treatment decisions together, which enhances patients' trust and sense of participation (Taberna et al., 2020). MDT will involve patients and their families in the diagnosis and treatment process, helping them understand their own conditions and thus persist in completing relatively complex treatments. This patient-centered model can not only bring better therapeutic effects, but also make patients feel more secure during the medical process and have higher overall satisfaction (Bisceglia et al., 2024).
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