Cancer Genetics and Epigenetics, 2025, Vol.13, No.6, 265-274 http://medscipublisher.com/index.php/cge 272 While helping to relieve pain, non-pharmaceutical intervention can also improve the quality of daily life of cancer patients, regulate their emotional state, and make them more willing to cooperate with treatment. Methods such as music therapy, mindfulness training and health guidance have been proven to alleviate anxiety, depression and fatigue that patients experience during treatment, thereby promoting overall recovery and emotional regulation ability. To enhance the application effect of non-pharmaceutical intervention, it is necessary to formulate unified operation norms, strengthen the training of relevant personnel, and integrate these therapies into the regular diagnosis and treatment process. Future research should focus more on conducting large-scale and well-designed clinical studies in different patient groups. In addition, medical institutions should also form multidisciplinary collaborative teams and clearly define specific nursing procedures to ensure that these intervention methods can safely, effectively and fairly benefit patients. Acknowledgments The authors extend sincere thanks to Mr. Cai for her feedback on the manuscript. Conflict of Interest Disclosure The authors affirm that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References Azizoddin D., Adam R., Kessler D., Wright A., Kematick B., Sullivan C., Zhang H., Hassett M., Cooley M., Ehrlich O., and Enzinger A., 2021, Leveraging mobile health technology and research methodology to optimize patient education and self-management support for advanced cancer pain, Supportive Care in Cancer, 29: 5741-5751. https://doi.org/10.1007/s00520-021-06146-4 Belayneh M., Fainsinger R., Nekolaichuk C., Muller V., Bouchard S., Downar J., Galloway L., Ghosh S., Hawley P., Herx L., Kmet A., and Lawlor P., 2022, Edmonton classification system for cancer pain: comparison of pain classification features and pain intensity across diverse palliative care settings in canada, Journal of Palliative Medicine, 26(3): 366-375. https://doi.org/10.1089/jpm.2022.0187 Carney L., Park C., and Hingorany P., 2023, The mechanisms of mindfulness-based stress reduction and mindfulness-based cognitive therapy for cancer patients and survivors: a systematic review, Psychology of Consciousness, 15: 10-37. https://doi.org/10.1037/cns0000362 Chang Y., Tseng T., Lin G., Hu W., Wang C., and Chang Y., 2023, Immediate impact of mindfulness-based cognitive therapy (MBCT) among women with breast cancer: a systematic review and meta-analysis, BMC Women's Health, 23(1): 331. https://doi.org/10.1186/s12905-023-02486-x Chapman E., Edwards Z., Boland J., Maddocks M., Fettes L., Malia C., Mulvey M., and Bennett M., 2020 Practice review: evidence-based and effective management of pain in patients with advanced cancer, Palliative Medicine, 34: 444-453. https://doi.org/10.1177/0269216319896955 Chayadi E., Baes N., and Kiropoulos L., 2022, The effects of mindfulness-based interventions on symptoms of depression anxiety and cancer-related fatigue in oncology patients: a systematic review and meta-analysis, PLoS ONE, 17(7): e0269519. https://doi.org/10.1371/journal.pone.0269519 Dave P., 2024, Recommendations for pain management in cancer patients, Asian Journal of Pharmaceutical Research and Development, 12(2): 7-12. https://doi.org/10.22270/ajprd.v12i2.1339 Deng G., 2019, Integrative medicine therapies for pain management in cancer patients, Cancer Journal, 25(5): 343-348. https://doi.org/10.1097/ppo.0000000000000399 Ehrlich O., Lackowski A., Glover T., and Vallerand A., 2024, Use of goals in cancer pain management: a systematic review, Journal of Pain and Symptom Management, 68(3): e194-205. https://doi.org/10.1016/j.jpainsymman.2024.05.026 Epstein A., Liou K., Romero S., Baser R., Wong G., Xiao H., Mo Z., Walker D., MacLeod J., Li Q., Barton-Burke M., Deng G., Panageas K., Farrar J., and Mao J., 2023, Acupuncture vs massage for pain in patients living with advanced cancer, JAMA Network Open, 6(11): e2342482. https://doi.org/10.1001/jamanetworkopen.2023.42482 Faria M., Teixeira M., Pinto M., and Sargento P., 2024, Efficacy of acupuncture on cancer pain: a systematic review and meta-analysis, Journal of Integrative Medicine, 22(3): 235-244. https://doi.org/10.1016/j.joim.2024.03.002 Ge L., Wang Q., He Y., Wu D., Zhou Q., Xu N., Yang K., Chen Y., Zhang A., Hua H., Huang J., Hui K., Liang F., Wang L., Xu B., Yang Y., Zhang W., Zhao B., Zhu B., Guo X., Xue C., Zhang H., Xue C., Zhang H., Guo X., He R., Pan Z., Yang L., Liu S., Li J., Hou L., Zhang Q., Lai H., Chen X., Deng X., and Kang F., 2022, Acupuncture for cancer pain: an evidence-based clinical practice guideline, Chinese Medicine, 17(1): 8.
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