CGE_2025v13n5

Cancer Genetics and Epigenetics, 2025, Vol.13, No.5, 236-244 http://medscipublisher.com/index.php/cge 244 Wang M., Li C., Liang L., Xing H., Sun L., Quan B., Wu H., Xu X., Wu M., Pawlik T., Lau W., Shen F., and Yang T., 2020, Early and late recurrence of hepatitis B virus-associated hepatocellular carcinoma, The Oncologist, 25(10): e1541-51. https://doi.org/10.1634/theoncologist.2019-0944 Wang Q., Zhou D., Wu F., Liang Q., He Q., Peng M., Yao T., Hu Y., Qian B., Tang J., Wang X., Liu W., Yu F., and Chen C., 2021, Immune microenvironment signatures as biomarkers to predict early recurrence of stage Ia-b lung cancer, Frontiers in Oncology, 11: 680287. https://doi.org/10.3389/fonc.2021.680287 Wang X., Yu Y., Tao Y., Wang Y., Zhang C., Cui Y., and Zhou Y., 2023, Clinical-radiological characteristic for predicting ultra-early recurrence after liver resection in solitary hepatocellular carcinoma patients, Journal of Hepatocellular Carcinoma, 10: 2323-2335. https://doi.org/10.2147/JHC.S434955 Wu J., Zhang C., Chan Y., Lu Y., Tan H., Feng Y., and Wang N., 2022, Preoperative immune cells infiltration in the tumor microenvironment as a prediction and prognostic factor for postoperative recurrence in hepatocellular carcinoma, SSRN Electronic Journal, 10: 4153442. https://doi.org/10.2139/ssrn.4153442 Wu W., Wang J., Chen F., Wang X., Lan B., Fu R., Wen H., Chen F., Hong W., Tang T., He Y., Chen G., Zhou J., Piao H., Chen D., and Lin S., 2025, Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma, Molecular Oncology, 19: 2388-2411. https://doi.org/10.1002/1878-0261.70012 Xie D., Liu Y., Xu F., Dang Z., Li M., Zhang Q., and Dang Z., 2025, Immune microenvironment and immunotherapy in hepatocellular carcinoma: mechanisms and advances, Frontiers in Immunology, 16: 1581098. https://doi.org/10.3389/fimmu.2025.1581098 Yang W., Yu L., Tian T., Anli J., Te L., Wei C., Tong L., Lin D., Hao W., Pan B., Beili W., Jian Z., Jia F., Yang X., and Wei G., 2024, Serum Galectin-9 mirrors immune-evasive microenvironment and predicts early recurrence in hepatocellular carcinoma, Gene, 942: 149184. https://doi.org/10.1016/j.gene.2024.149184 Yang Y., Chen Y., Ye F., Cao X., Xin Y., Wang Y., Lei Y., Li X., Feng D., Zhou X., and Fan Q., 2020, Late recurrence of hepatocellular carcinoma after radiofrequency ablation: a multicenter study of risk factors patterns and survival, European Radiology, 31: 3053-3064. https://doi.org/10.1007/s00330-020-07460-x Yeo A., Rawal S., Delcuze B., Christofides A., Atayde A., Strauss L., Balaj L., Rogers V., Uhlmann E., Varma H., Carter B., Boussiotis V., and Charest A., 2022, Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression, Nature Immunology, 23: 971-984. https://doi.org/10.1038/s41590-022-01215-0 Yin Y., Feng W., Chen J., Chen X., Wang G., Wang S., Xu X., Nie Y., Fan D., Wu K., and Xia L., 2024, Immunosuppressive tumor microenvironment in the progression metastasis and therapy of hepatocellular carcinoma: from bench to bedside, Experimental Hematology and Oncology, 13(1): 72. https://doi.org/10.1186/s40164-024-00539-x You G., Park S., Cho S., Cho S., Koh Y., Lee C., Jo H., Choi S., and Yoon J., 2025, Extrahepatic recurrence after surgical resection of hepatocellular carcinoma without intrahepatic recurrence: a multi-institutional observational study, Cancers, 17(9): 1417. https://doi.org/10.3390/cancers17091417 Yu J., Fu L., Wu R., Che L., Liu G., Ran Q., Xia Z., Liang X., and Zhao G., 2025, Immunocytes in the tumor microenvironment: recent updates and interconnections, Frontiers in Immunology, 16: 1517959. https://doi.org/10.3389/fimmu.2025.1517959 Zhao Z.Y., Wu H.D., Sun H.M., and Zhao Y., 2024, Genetic mutation profiles of colorectal cancer and their prospects in diagnosis, Cancer Genetics and Epigenetics, 12(6): 317-328. https://doi.org/10.5376/cge.2024.12.0030

RkJQdWJsaXNoZXIy MjQ4ODYzNA==