Cancer Genetics and Epigenetics, 2025, Vol.13, No.5, 215-223 http://medscipublisher.com/index.php/cge 222 Looking to the future, end-of-life care for patients with advanced cancer may be influenced in multiple aspects: senior nurses will be more deeply involved, interdisciplinary teams will further expand, and greater emphasis will be placed on the early formulation of care plans and patients' autonomous choices. To address cultural differences, uneven resource distribution and constantly changing demands, continuous research, policy improvement and public education are still indispensable. The ultimate goal is to achieve empathetic, personalized and value-oriented end-of-life care. Acknowledgments The author extends sincere thanks to two anonymous peer reviewers for their feedback on the manuscript. Conflict of Interest Disclosure The author affirms that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References Agarwal R., and Epstein A., 2018 Advance care planning and end-of-life decision making for patients with cancer, Seminars in Oncology Nursing, 34(3): 316-326. https://doi.org/10.1016/j.soncn.2018.06.012 Chen Y., Kao Y., Lin K., and Chang H., 2024 The effect of multidisciplinary care on polypharmacy in advanced cancer patients near the end of life, The European Journal of Public Health, 34(Supplement_3): ckae144-880. https://doi.org/10.1093/eurpub/ckae144.880 Crawford G., Dzierżanowski T., Hauser K., Larkin P., Luque-Blanco A., Murphy I., Puchalski C., and Ripamonti C., 2021, Care of the adult cancer patient at the end of life: ESMO clinical practice guidelines, ESMO Open, 6(4): 100225. https://doi.org/10.1016/j.esmoop.2021.100225 Du J., An Z., Wang C., and Yu L., 2024, Nurse’ self-regulation after engaging in end-of-life conversations with advanced cancer patients: a qualitative study, BMC Nursing, 23(1): 344. https://doi.org/10.1186/s12912-024-02016-6 Ghezelsefli Z., Ahmadi F., and Mohammadi E., 2020, End-of-life care provided for cancer patients, Holistic Nursing Practice, 34: 210-220. https://doi.org/10.1097/HNP.0000000000000391 Goswami P., 2022, Impact of advance care planning and end-of-life conversations on patients with cancer: an integrative review of literature, Journal of Nursing Scholarship, 55(1): 272-290. https://doi.org/10.1111/jnu.12804 Gao L.P., He Y.L., Li Q., and Huang Y.L., 2025, Research progress on family-involved discharge care models for cancer patients, Cancer Genetics and Epigenetics, 13(3): 145-153. https://doi.org/10.5376/cge.2025.13.0015 Hua M., Guo L., Ing C., Lackraj D., Wang S., and Morrison R., 2024, Specialist palliative care use and end-of-life care in patients with metastatic cancer, Journal of Pain and Symptom Management, 67(5): 357-365. https://doi.org/10.1016/j.jpainsymman.2024.01.029 Haung M.Z., Zhu L., and Huang Y.L., 2024, Study on the application and impact of smart health devices in community care, International Journal of Clinical Case Reports, 14(6): 338-349. https://doi.org/10.5376/ijccr.2024.14.0033 Jeong M., Song C., and Park S., 2023, Implementation and evaluation of an end-of-life care education program for oncology nurses working in medical-surgical wards: a quasi-experimental study, Heliyon, 9(4): e14096. https://doi.org/10.1016/j.heliyon.2023.e14096 Kenny P., Street D., Hall J., Agar M., and Phillips J., 2021, Valuing end-of-life care for older people with advanced cancer: is dying at home important?, The Patient-Patient-Centered Outcomes Research, 14: 803-813. https://doi.org/10.1007/s40271-021-00517-z Koroukian S., Douglas S., Vu L., Fein H., Gairola R., Warner D., Schiltz N., Cullen J., Owusu C., Sajatovic M., and Rose J., 2023, Incidence of aggressive end-of-life care among older adults with metastatic cancer living in nursing homes and community settings, JAMA Network Open, 6(2): e230394. https://doi.org/10.1001/jamanetworkopen.2023.0394 Kwon Y., Hu X., Shi K., Zhao J., Jiang C., Fan Q., Han X., Zheng Z., Warren J., and Yabroff K., 2025, Contemporary patterns of end-of-life care among medicare beneficiaries with advanced cancer, JAMA Health Forum, 6(2): e245436. https://doi.org/10.1001/jamahealthforum.2024.5436 Laryionava K., and Winkler E., 2021, Dealing with family conflicts in decision-making in end-of-life care of advanced cancer patients, Current Oncology Reports, 23(11): 124. https://doi.org/10.1007/s11912-021-01122-x
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