Cancer Genetics and Epigenetics, 2025, Vol.13, No.5, 215-223 http://medscipublisher.com/index.php/cge 219 improve their quality of life, and make patients happier and more satisfied with care (Lee and Ramaswamy, 2020; Liu et al., 2024). Projects like Peaceful Hospice Care, which integrate health knowledge explanation, psychological and social support, and advance care planning, also make people feel that the effect of "passing away peacefully" is better, and also bring patients, their families, and caregivers closer together (Agarwal and Epstein, 2018; Trakoolngamden et al., 2025). The satisfaction of family members is closely related to whether the care respects the patient's wishes and whether the communication is smooth. Those overly aggressive end-of-life practices, such as repeated hospitalizations or registering for palliative care only at a very late stage of illness, often lead to a decline in caregiver satisfaction (Park et al., 2023; Kwon et al., 2025). Emphasizing the model of formulating care plans in advance and making joint decisions can better enhance trust and satisfaction among family members. It also indicates that good communication and comprehensive support are particularly important in end-of-life care (Goswami, 2022; Hua et al., 2024). 4.3 Utilization of medical resources and quality of death In the final stage of life, whether medical resources can be used reasonably is an important indicator for judging the quality of care. The practices of specialist palliative care and MDT can reduce overtreatment, such as shortening ICU stay and late chemotherapy, and also enable more people to enter hospice care, thereby improving the quality of the end-of-life stage (Park et al., 2023; Chen et al., 2024). These measures can also ensure that care is more in line with patients' thoughts, reduce unnecessary hospitalizations, and help patients pass away where they wish (Mitchell et al., 2020; Kenny et al., 2021). In contrast, overly intensive end-of-life care remains common, especially in hospitals and elderly care institutions, which often leads to more resource consumption but results in a worse death experience (Koroukian et al., 2023; Kwon et al., 2025). The community-based service model and multi-disciplinary team collaboration can make resource allocation more reasonable and support patients to spend their final days more peacefully and with dignity. It is important to continuously evaluate and improve these approaches, find the appropriate balance between resource utilization and the actual needs of patients, while ensuring that the care for advanced cancer truly focuses on improving the quality of the end of life (Crawford et al., 2021; Hua et al., 2024). 5 Limitations and Challenges 5.1 Insufficient medical resources and policy support The main difficulties that patients with advanced cancer encounter in end-of-life care are insufficient medical resources and inadequate policy support. Many medical systems lack funds, equipment and personnel, making it difficult to provide comprehensive palliative care and end-of-life services in various Settings, especially outside hospitals. The shortage of resources makes it difficult for patients to receive help from professional teams, resulting in untimely symptom management. Medical staff are more likely to adopt active treatment methods that do not conform to the patients' wishes (Kwon et al., 2025). The lack of a sound policy framework exacerbates these problems, as there are usually no unified standards and incentives to promote early palliative care or support community care models (Mitchell et al., 2020; Tanaka et al., 2022). The insufficiency of policies will also affect the development of multidisciplinary nursing and family care models, making it difficult for these models to be maintained in the long term. Without clear support from the government or institutions, it is difficult for new care methods to expand their scope, and the quality gap of care among different regions and different groups of people has always existed. The policy has not promoted support for training, resource allocation and care coordination, which limits the ability of medical personnel to provide stable and high-quality hospice care to patients with advanced cancer (Crawford et al., 2021; Hua et al., 2024). 5.2 Insufficient professional capabilities and service systems Another major problem is the insufficient professional ability of medical staff and the lack of systematic services. Many nurses and general practitioners reported that they were inadequately trained in hospice care, especially in symptom management, communication and psychological support (Shahmohammadi et al., 2024). This training
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