Computational Molecular Biology
            
            
              11
            
            
              addition, functional enrichment analysis on the
            
            
              proteins in this network reveals these proteins are
            
            
              potential cancer-related genes (Table 2).
            
            
              
                2 Discussion
              
            
            
              In this study, we mainly focus on differentially
            
            
              methylated CpG sites among cancers. Through a
            
            
              Figure 4 Protein interaction sub-network based on huamn protein interaction network
            
            
              Note: The proteins coded by the genes with
            
            
              
                bona fide
              
            
            
              C-DMSs are in orange, and their nearest neighbor proteins in green
            
            
              Computational
            
            
              Molecular Biology