International Journal of Clinical Case Reports 2017, Vol.7, No.7, 28-32
28
Case Report Open Access
Contemporary Dental Management of a Patient with Osteogenesis Imperfecta
(OI)
Pallavi Sinha
1
, Abhishek Singh Nayyar
1
, Abhishek Karan
2
, Veena R.
3
, Karunakar M.N.
3
1 Department of Oral and Maxillofacial Medicine and Radiology, Saraswati Dhanwantari Dental College and Hospital and Post-Graduate Research Institute,
Parbhani, Maharashtra, India
2 Department of Oral and Maxillofacial Surgery, Saraswati Dhanwantari Dental College and Hospital and Post-Graduate Research Institute, Parbhani,
Maharashtra, India
3 Department of Oral and Maxillofacial Medicine and Radiology, Oxford Dental College and Hospital, Bangalore, Karnataka, India
Corresponding author email
International Journal of Clinical Case Reports 2017, Vol.7, No.7 doi
Received: 19 May, 2017
Accepted: 19 Jun., 2017
Published: 23 Jun., 2017
Copyright © 2017
Sinha et al., This is an open access article published under the terms of the Creative Commons Attribution License, which permits
unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:
Sinha P., Nayyar A.S., Karan A., Veena R., and Karunakar M.N., 2017,
Contemporary dental management of a patient with Osteogenesis imperfecta (OI),
7(7): 28-32 (doi
Abstract
Osteogenesis imperfecta (OI) is a characteristic bone disease which affects an individual through birth or, early in life.
This disease has a range of morbidity and mortality depending on the type of the disease. This case report presents the difference in
approach to management of a simple dental condition in a patient with OI highlighting the importance of a thorough history-taking in
revealing the underlying systemic condition. The report, also, discusses the pathogenesis, types, clinical features, dental
manifestations and special considerations in patients with OI.
Keywords
Osteogenesis imperfecta (OI); Bone disease
Introduction
Osteogenesis imperfecta (OI) is a characteristic bone disease which affects an individual through birth or, early in
life. This disease has a range of morbidity and mortality depending on the type of the disease. OI has a birth
prevalence of approximately 6-7/100,000. (van Dijk FS et al., 2011) The prevalence and incidence of OI types are
different from each other with OI type I and OI type IV accounting for considerably more than half of all the OI
cases reported. (van Dijk FS et al., 2011) The clinical symptoms vary and include multiple fractures which is most
commonly seen in type 2 in addition to blue sclerae, (scleral thinness allows the pigment of choroid to become
visible), advancing deafness, beading of the ribs, osteoporosis, and deformity of the skull. The present case report
presents the difference in approach to management of a simple dental condition such as chronic irreversible
pulpitis in a patient with OI highlighting the importance of a thorough history-taking in revealing the underlying
systemic condition. The report, also, discusses the pathogenesis, types, clinical features, dental manifestations and
special considerations in patients with OI.
1 Case Report
A male child patient aged 3 years (Figure 1) visited the Outpatient Department (OPD) with a chief complaint of
pain in upper front tooth region since one week. The patient's parent stated that the child complained of pain
intermittently which occurred while having food and remained for a while and that he could localize the offending
tooth. At the time of examination, the patient was afebrile and there were no associated systemic symptoms. It was
patients first dental visit. During interview of patient’s past medical history with the parents, they casually
disclosed that the child had suffered several fractures of his long bones within a span of the last one year while
playing. The child was under treatment for the same and was, also, on calcium supplements. The patient's parents
gave history of consanguineous marriage. There was absent positive history of repeated fractures in the family in
childhood. On general physical examination, the patient was moderately built and nourished and gait was close to
normal while knock knees were evident (Figure 2). A very slight bluish tinge was appreciated in the sclerae
(Figure 3). On intra oral examination, there was loss of crown structure with discoloration in relation to tooth # 51,
52, 61 and 62. Intra-oral peri-apical (IOPA) radiographs were advised in the same region for the above mentioned
