CGE-2017v5n5 - page 6

Cancer Genetics and Epigenetics 2017, Vol.5, No.5, 25-27
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demonstrated situated at the right side of the tumor, and was compressed by the mass and shifted off the midline.
Furthermore, the trianglular solid compartment was pointing into the CPA, with strong association with the left
acoustic nerve root. Despite these evidences may be not enough to suggest the tumor arising from the nerve, they
indicated the origination from the CPA region.
Apart from the site, some radiological characteristics are worth to note, i.e., the correlation between the MRI
intense signals and the tumor characteristics. Reviewing of the literature revealed some distinctive features of PS
including the multinodular architecture and the individual thin capsule, but rarely any case of its radiological and
pathological relation was detected. MRI images showed the tumor was solid-cystic due to the heterogeneous
intense signals presented. Moreover, these cystic compartments presented with slight hyperintense signal
compared with cerebral spinal fluid (CSF) on T2-weighted images; and solid compartments showed slight hyper
signal intensity on T2-weighted and FLAIR images compared with parenchyma. Taking the radiological findings
for this tumor into consideration, the diagnosis of schwannoma was made. As schwannoma is a benign,
encapsulated nerve sheath tumour composed of primarily Schwann cells in a poorly collagenised stroma, we can
postulate the hypothesis that MRI images might indicate the essential pathological features of conventional as
well as plexiform schwannoma including compact and/or loose texture (Antoni A and/ or B tissues) (Berg et al.,
2008).
3 Conclusion
In summary, we describe the first case of a facial nerve originated and CPA PS. MRI images might indicate the
essential pathological features of conventional as well as plexiform schwannoma.
Authors’ contributions
Liang Zong-hui conceived and designed the work that led to the submission. Dou Ya-fang and Liang Zong-hui evaluated images and
analyzed data. Dou Ya-fang completed the writing of the article. Liang Zong-hui revised the paper. All authors participated in paper
writing and approved the final manuscript.
Acknowledgments
This work was supported by the Shanghai Jing’an District Health System talent training Plan discipline leader, project number
JWRC2014D04.
Reference
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1,2,3,4,5 7,8
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