IJCCR 2013, Vol.3, No.2, 7
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examination, using Bronchoscopy methods. The 2
circular rings represent the outer and the midestinal
layers of the bronchus, respectively. The zagged
interior alias lumen is the internal configuration, layed
with heavy stringy mucosa. It shows constriction of
the air way. We have drawn a constant area circle
within the lumen and juxtaposed it into all the
conditions, to demonstrate our findings. Figure 6 is of
the same patient after inhalation of steroidal
broncho-dilator. We can see the lumen has widen.
Figure 7, is that of the same patient viewed during the
pass of a weather system {approx. 980 hPa, central
core pressure}. yet he was not requiring any drugs,
nor was he given any, neither was he having any
spasm. No wheezing. No creepeting (saturated air at
Figure 5 Graphical representation of the Bronchus of a asthma
patient (Jagatsingpur, Odisha, 03-07-2006, near Paradip)
Figure 6 A patient after inhalation of steroidal broncho-dilator
Figure 7 A patient viewed during the pass of a weather system
{
approx. 980 hPa, central core pressure}
ambient). He was expirating at near peak volumes
with easy, and was happy, reporting a feel good factor.
However on performing a Bronchoscopy, it was noted,
his airways had no perceptible increase in lumen size.
It is a known fact of clinical science, that, spray based
medicines are composed of micro particulates.
Particulates of the size <0.5 m gets exhaled. Only
10%
of the inhaled spray comprising of particulates
of the range 1~5 m reach the bronchus and get settled.
That, 90% of the inhaled drug gets deposited (wasted)
in the region of the fossa i.e., oropharynx (Clark and
Godfrey, 1977). This means, when the outside
pressure reduces, expiration volumes increase,
followed by efficiency and generally in the overall
timing, aided and abetted by a never before like, ‘feel
good factor’. In other words, the barometric low
assists the lungs perform better, at the alveoli level, by
catalysing a well timed inhalation-expiration
involuntary smooth muscle function, although the
bronchus may be constricted and\or loaded with
mucus exudates. This is because atmosphereic fluid is
highly compressible. Hence we aver, that, (i) that there
is suo-sponte signal based balance between the
mechanosensitivity pulmonary C-fiber receptors and
the chemosensitive bronchial C-fiber receptors. As the
alveoli expirates well {exhausts the used gases} the
chemosensitive bronchial C-fiber receptors {snooze}
do not cause any constriction (ii) the pulmonary-
thorax mechanical miss-match is initially triggered
primarily due to impaired expiration at normal
atmospheric pressure (iii) is accentuated by an
involuntary constriction of the air-ways to force
enhance expiration, which gradually up-regulates into
a self infracting cadence, all being pseudo. Yet altered
heart rate (substantive) creates clinical crisis. At
normal\heightened pressure, the lungs are auto
inflated and loaded. Expiration cadence miss-match
interferes with the inhalation performance cadence,
triggering a mild anoxia. It is the failure to expirate at
optimum/required volumes that prima-facie is the
initial-principal cause of the onset of the pseudo
distress syndrome, otherwise known as ‘spasms’. At
heightened state/extended periods, such mechano
aberration caused pseudo distress, shortened breath,
posits as life threatening. Atmospheric low\lack of
opposition to expiration is effective anti-dote. The
TSCS have no perceptible effect on the lumen
diameter and does not work as do broncho-dilators.