IJCCR 2013, Vol.3, No.1, 1
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http://ijccr.sophiapublisher.com
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medical guidelines and the recommended intake is
2
~3 meals consisting of 150~200 kcal per meal. The
data regarding time gap between meals was compiled
and analysed to find how well the subjects were under
the specified medical guidelines. From Figure 1 it can
be seen that as majority of the subjects i.e. 37 didn’t
consume the morning mid-day meal, the time gap was
of around 4~5 hours, which was inappropriate for
maintaining the blood glucose level and ultimately
would lead to diabetic complications in the long run.
Figure 1 The time gap between meals consumed in a day
Palate preference -32 out of 40 subjects preferred a
spicy taste in their mid-day meal and rest 8 preferred
sweet taste. This data was further statistically analysed
at a specified confidence level so that the product
could be formulated on the obtained conclusions
(
Table 1).
It was observed that the calculated ? 2 value i.e. 14.4
was significantly greater than the tabular ? 2 values of
3.84
and 6.63 (p<0.05 and p<0.01). It indicated that
the palate preference for spicy taste was more than
sweet taste, hence formulation of the proposed product
was thus carried out on these lines.
1.2
Analysis of Clinical Trials
The means of the individual blood glucose level types
i.e. FBS and PP2 were calculated and were compared
with the pre-laid safe ranges. The data of mean blood
glucose levels of subjects is given in Table 2. It can be
observed that the results for mean blood-glucose
levels of the 40 control subjects were almost in
accordance with the pre-laid limits. The subjects not
being under 24
-
hour monitoring for the clinical trial,
some discrepancy was expected in their diet intake,
though each individual was given specified instructions
and their diet intake was asked to be noted down in
the personal forms provided, for each day.
The results of paired T test for the blood glucose
levels of subjects are given in Table 3. There was no
significant difference between the fasting blood
glucose levels (FBS_D1, FBS_D2, FBS_D3,
FBS_D4). This meant that the subjects were in control
of their blood sugar levels and hence eligible for the
trials and also the result analysis.
There was no significant difference between the PP2
BS levels of day 3 and day 4 which means that the
subjects had constant blood glucose levels on both the
days with formulated snack. However there was a
significant difference (30 mg/dl negative shift)
between the PP2BS levels of subjects when they
consumed their regular meal in comparison with the
formulated snack.
1.3
Response of the Formulated Snack
All variants of the snack were found to be successful
in lowering the blood glucose levels of the subjects
which is indicated by clinical trial analysis. This
showed that the formulated RTS convenience snack
had a very high probability of having a low glycemic
index compared to the fried snacks available in the
market. An oral response from the subjects showed
that the snack had satiety of almost 2 hours (Table 4).
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Conclusions
From the present investigation, it can be concluded
that there was a significant drop in the blood glucose
levels of the subjects after they consumed the
formulated snack i.e. around 30 mg/dl. Validation tests
showed that the calorie content of 1 serving (40 g) was
well under recommended guidelines i.e. 175 kcal. The