International Journal of Clinical Case Report 2016, Vol.6, No.19, 1-3
1
A Letter Open Access
Pheochromocytoma and Von Recklinghausen Disease Revealed by Adrenal
Incidentaloma
M. A. Amani , N. Medjadi, B. Benlazaar
Department of Endocrinology and Diabetology 1
ST
November Hospital Oran, Algeria
Corresponding author email
International Journal of Clinical Case Report
2016, Vol.6, No.19 doi
Received: 22 Feb., 2016
Accepted: 28 Mar., 2016
Published: 5 May, 2016
This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article
:
Amani M.A., Medjadi N., and Benlazaar B., 2016, Pheochromocytoma and Von Recklinghausen Disease Revealed by Adrenal Incidentaloma, International
Journal of Clinical Case Report, 6(19): 1-3 (doi
Abstract
Adrenal incidentalomas are discovered incidentally during a radiological examination of the abdomen whatever the
reason justifying this exploration.
We report the case of a 37 years old woman with no particular family history and who consulted for a right adrenal incidentaloma
discovered during an abdominal ultrasound performed for vomiting. Clinical examination revealed a blood pressure-110/70 mmHg, a
Menard triad (headaches, palpitations, sweating), a multiheteronodular goiter without signs of thyroid dysfunction, café-au-lait spots
and cutaneous neurofibromas and diffuses lentiginous.
Laboratory tests confirmed the secretory nature of the mass. A radiological assessment with an abdominopelvic computed
tomography (CT) scan showed a right adrenal tissue mass measuring 47×48×38 mm. The MIBG scintigraphy confirmed the
neuroendocrine nature of the mass and the absence of other sites.
Keywords
Adrenal incidentaloma; Pheochromocytoma; von Recklinghausen disease; Adrenalectomy
1 Introduction
Adrenal incidentalomas are discovered incidentally during a radiological examination of the abdomen whatever
the reason justifying this exploration (Tabuchi et al., 2015). Furthermore pheochromocytoma, the etiologies of
these incidentalomas are various (Tabuchi et al., 2015). Pheochromocytomas are neuroendocrine tumors
developed at the expense of cells derived from neural crest. Pheochromocytomas can be sporadic or familial and
then be isolated or integrated into multiple endocrine neoplasia (MEN type 1 and 2), phacomatosis (von
Recklinghausen disease) or von Hippel Lindau disease (VHL).
2 Observation
We report the case of a 37 years old woman with no particular family history and who consulted for a right
adrenal incidentaloma discovered during an abdominal ultrasound performed for vomiting. Clinical examination
revealed a blood pressure-110/70 mmHg, a Menard triad (headaches, palpitations, sweating), a multiheteronodular
goiter without signs of thyroid dysfunction, café-au-lait spots and diffuses lentiginous and cutaneous
neurofibromas (Figure 1, 2, 3).
Café-au-lait spots
Figure 1 Cutaneous lesions: café-au-lait spots
