Molecular Pathogens, 2025, Vol.16, No.6, 266-275 http://microbescipublisher.com/index.php/mp 273 by relying on a single discipline - plant breeding, microbial ecology, bioinformatics, and even field management experience all need to be united as one. If these forces can truly be combined in the future, microbiome-assisted breeding will not only make crops more resistant to diseases but also reduce the use of pesticides, helping agriculture gain more confidence in responding to climate change and pathogen evolution, and providing a more stable guarantee for food security. Acknowledgements In the course of completing this study, we would like to thank the members of my research group for their support and collaboration. We also wish to express my gratitude to the two experts for their valuable review comments. Conflict of Interest Disclosure The authors confirm that the study was conducted without any commercial or financial relationships and could be interpreted as a potential conflict of interest. References Afridi M., Fakhar A., Kumar A., Ali S., Medeiros F., Muneer M., Ali H., and Saleem M., 2022, Harnessing microbial multitrophic interactions for rhizosphere microbiome engineering, Microbiological Research, 265: 127199. https://doi.org/10.1016/j.micres.2022.127199 Anderson H., Cagle G., Majumder E., Silva E., Dawson J., Simon P., and Freedman Z., 2024, Root exudation and rhizosphere microbial assembly are influenced by novel plant trait diversity in carrot genotypes, Soil Biology and Biochemistry, 197: 109516. https://doi.org/10.1016/j.soilbio.2024.109516 Araujo A., De Araujo Pereira A., Costa D., De Medeiros E., Araujo F., Sharma S., and Mendes L., 2024, Enhancing plant resilience to pathogens through strategic breeding: harnessing beneficial bacteria from the rhizosphere for progeny protection, Rhizosphere, 30: 100890. https://doi.org/10.1016/j.rhisph.2024.100890 Badar A., Aqueel R., Nawaz A., Ijaz U., and Malik K., 2025, Microbiota transplantation for cotton leaf curl disease suppression—core microbiome and transcriptome dynamics, Communications Biology, 81(9): 302. https://doi.org/10.1038/s42003-025-07812-7 Berendsen R., Vismans G., Yu K., Song Y., De Jonge R., Burgman W., Burmølle M., Herschend J., Bakker P., and Pieterse C., 2018, Disease-induced assemblage of a plant-beneficial bacterial consortium, The ISME Journal, 12: 1496-1507. https://doi.org/10.1038/s41396-018-0093-1 Chauhan P., Sharma N., Tapwal A., Kumar A., Verma G., Meena M., Seth C., and Swapnil P., 2023, Soil microbiome: diversity benefits and interactions with plants, Sustainability, 15(19): 14643. https://doi.org/10.3390/su151914643 Darshita S., James S., Jyoti D., Ratul N., and Munmi B., 2025, Advancements in induced systemic resistance: mechanisms applications and integration for sustainable crop protection and climate adaptation, Plant Science Today, 12(3): 1-17. https://doi.org/10.14719/pst.7976 Du X., Sun T., Xu W., Zhu T., Wang Q., Gu P., and Lu J., 2025, Multi-omics analysis reveals the specific role of biocontrol reagents against tomato bacterial wilt, Frontiers in Plant Science, 16: 1620460. https://doi.org/10.3389/fpls.2025.1620460 Dwivedi S., Vetukuri R., Kelbessa B., Gepts P., Heslop-Harrison P., Araujo A., Sharma S., and Ortiz R., 2025, Exploitation of rhizosphere microbiome biodiversity in plant breeding, Trends in Plant Science, 30(9): 1033-1045. https://doi.org/10.1016/j.tplants.2025.04.004 Ferrarezi J., Defant H., De Souza L., Azevedo J., Hungria M., and Quecine M., 2023, Meta-omics integration approach reveals the effect of soil native microbiome diversity in the performance of inoculant Azospirillum brasilense, Frontiers in Plant Science, 14: 1172839. https://doi.org/10.3389/fpls.2023.1172839 Güney İ., Derviş S., Özer G., Aktaş H., and Keske M., 2024, Determination of antagonistic activities of endophytic bacteria isolated from different wheat genotypes against Fusarium culmorum, Uluslararası Tarım ve Yaban Hayatı Bilimleri Dergisi, 10(1): 96-116. https://doi.org/10.24180/ijaws.1386741 Kusstatscher P., Adam E., Wicaksono W., Bernhart M., Olimi E., Mü ller H., and Berg G., 2021, Microbiome-assisted breeding to understand cultivar-dependent assembly in Cucurbita pepo, Frontiers in Plant Science, 12: 642027. https://doi.org/10.3389/fpls.2021.642027 Lazcano C., Boyd E., Holmes G., Hewavitharana S., Pasulka A., and Ivors K., 2021, The rhizosphere microbiome plays a role in the resistance to soil-borne pathogens and nutrient uptake of strawberry cultivars under field conditions, Scientific Reports, 11: 3188. https://doi.org/10.1038/s41598-021-82768-2
RkJQdWJsaXNoZXIy MjQ4ODYzNA==