MMR_2024v14n1

Molecular Microbiology Research 2024, Vol.14, No.1, 1-9 http://microbescipublisher.com/index.php/mmr 7 With the development of molecular biology and immunology, modern diagnostic methods have been further improved. For example, PCR technology can rapidly and accurately diagnose Salmonella infection by detecting the genes of Salmonella. Similarly, immunological methods can also detect the level of Salmonella antibodies in patients to determine the presence of Salmonella infection. In addition to traditional diagnostic methods, there are also new technologies being studied, such as mass spectrometry analysis and fluorescence spectroscopy analysis. The advantages of these methods are fast speed, high sensitivity, good specificity, but they still need further validation and application. Currently, the diagnosis of Salmonella infection is constantly developing and improving. Although traditional diagnostic methods remain important diagnostic tools, the development of modern technology will provide more choices and more efficient methods for the diagnosis of Salmonella infection. 4.2 Treatment methods for Salmonella infection The treatment methods for Salmonella infection mainly include antibiotic therapy and supportive care. Currently, commonly used antibiotics include fluoroquinolones, cephalosporins, aminoglycosides, and macrolides. These antibiotics can treat Salmonella infection by inhibiting the growth and reproduction of Salmonella. The choice of antibiotics should be based on the drug sensitivity of Salmonella and the clinical condition of the patient (Figure 3). During treatment, adjustments and monitoring should be made based on the patient's condition and adverse drug reactions. Figure 3Salmonelladetection and culture (GB 4789.4-2010 Food Microbiology Examination - Salmonella Testing) Besides antibiotic therapy, supportive care is also an important treatment for Salmonella infection. Supportive care plays an important role in the treatment of Salmonella infection. Salmonella is a type of bacteria that can cause food poisoning or Salmonella infection, usually manifesting as symptoms such as diarrhea, fever, and vomiting. In addition to drug treatment targeting the pathogen, supportive care is one of the key methods to help patients relieve symptoms and promote recovery. Supportive care includes maintaining water and electrolyte balance, correcting malnutrition, and managing symptoms. For example, diarrhea and vomiting can lead to fluid loss and cause dehydration and electrolyte disorder,so providing sufficient fluids and appropriate electrolyte supplements can help maintain balance in the body. Salmonella infection may affect appetite and lead to inadequate nutritional intake. Therefore, providing easily digestible foods and maintaining adequate nutritional intake can help accelerate recovery. Additionally, appropriate medications can help relieve pain and fever, improving patient comfort. During the infection period, proper isolation and rest can help the body fully resist the infection and promote recovery. During treatment, the patient's condition and vital signs should be closely monitored, and complications should be corrected and managed in a timely manner (Wang et al., 2020). In recent years, some new treatment methods are being studied, such as vaccines and immunotherapy. Vaccines can prevent Salmonella infection by stimulating the immune response of the body. Currently, there are some

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