Bt_2025v16n2

Bt Research 2025, Vol.16, No.2, 55-62 http://microbescipublisher.com/index.php/bt 62 Mendoza-Almanza G., Esparza-Ibarra E., Ayala-Luján J., Mercado-Reyes M., Godina-González S., Hernández-Barrales M., and Olmos-Soto J., 2020, The cytocidal spectrum of Bacillus thuringiensis toxins: from insects to human cancer cells, Toxins, 12(5): 301. https://doi.org/10.3390/toxins12050301 Olsen K., Daly J., Holt H., and Finnegan E., 2005, Season-long variation in expression of Cry1Ac gene and efficacy of Bacillus thuringiensis toxin in transgenic cotton against Helicoverpa armigera (Lepidoptera: Noctuidae), Journal of Economic Entomology, 98(3): 1007-1017. https://doi.org/10.1603/0022-0493-98.3.1007 Pacheco S., Cantón E., Zúñiga-Navarrete F., Pecorari F., Bravo A., and Soberón M., 2015, Improvement and efficient display of Bacillus thuringiensis toxins on M13 phages and ribosomes, AMB Express, 5: 73. https://doi.org/10.1186/s13568-015-0160-1 Reisig D., and Huseth A., 2025, Establishing best practices for insect resistance management: a new paradigm for genetically engineered toxins in cotton expressing Mpp51Aa2, Journal of Economic Entomology, 118: 1-8. https://doi.org/10.1093/jee/toae312 Soberón M., Pardo-López L., López I., Gómez I., Tabashnik B., and Bravo A., 2007, Engineering modified Bt toxins to counter insect resistance, Science, 318: 1640-1642. https://doi.org/10.1126/science.1146453 Svobodová Z., Habuštová S., Hutchison W., Hussein H., and Sehnal F., 2015, Risk assessment of genetically engineered maize resistant to Diabrotica spp.: influence on above-ground arthropods in the Czech Republic, PLoS One, 10(6): e0130656. https://doi.org/10.1371/journal.pone.0130656 Then C., 2009, Risk assessment of toxins derived from Bacillus thuringiensis- synergism, efficacy, and selectivity, Environmental Science and Pollution Research International, 17: 791-797. https://doi.org/10.1007/s11356-009-0208-3 Tiewsiri K., and Wang P., 2011, Differential alteration of two aminopeptidases N associated with resistance to Bacillus thuringiensis toxin Cry1Ac in cabbage looper, Proceedings of the National Academy of Sciences, 108: 14037-14042. https://doi.org/10.1073/pnas.1102555108 Torres J., Surya W., and Boonserm P., 2023, Channel formation in Cry toxins: an alphafold-2 perspective, International Journal of Molecular Sciences, 24(23): 16809. https://doi.org/10.3390/ijms242316809 Wang Z., Yang Y., Li S., Ma W., Wang K., Soberón M., Yan S., Shen J., Francis F., Bravo A., and Zhang J., 2024, JAK/STAT signaling regulated intestinal regeneration defends insect pests against pore-forming toxins produced by Bacillus thuringiensis, PLoS Pathogens, 20(1): e1011823. https://doi.org/10.1371/journal.ppat.1011823 Wei J., Zhang Y., and An S., 2019, The progress in insect cross-resistance among Bacillus thuringiensis toxins, Archives of Insect Biochemistry and Physiology, 102(3): e21547. https://doi.org/10.1002/arch.21547 Wu Y., 2014, Chapter six - detection and mechanisms of resistance evolved in insects to cry toxins fromBacillus thuringiensis, Advances in Insect Physiology, 47: 297-342. https://doi.org/10.1016/B978-0-12-800197-4.00006-3 Yu H., Li Y., and Wu K., 2011, Risk assessment and ecological effects of transgenic Bacillus thuringiensis crops on non-target organisms, Journal of Integrative Plant Biology, 53(7): 520-538. https://doi.org/10.1111/j.1744-7909.2011.01047.x Zhang W.F., 2024, CRISPR-based gene editing in Bt for improved insecticidal properties, Bioscience Methods, 15(5): 216-225. https://doi.org/10.5376/bm.2024.15.0022 Zhao S., Jiang D., Wang F., Yang Y., Tabashnik B., and Wu Y., 2020, Independent and synergistic effects of knocking out two ABC transporter genes on resistance to Bacillus thuringiensis toxins Cry1Ac and Cry1Fa in diamondback moth, Toxins, 13(1): 9. https://doi.org/10.3390/toxins13010009

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