Journal of Vaccine Research 2024, Vol.14, No.1, 17-26 http://medscipublisher.com/index.php/jvr 25 limitations in certain special circumstances, such as immunocompromised individuals and vaccine adverse reactions. Therefore, China needs to continuously refine vaccine manufacturing processes and immunization strategies to enhance the immunogenicity and reliability of vaccines. Additionally, China also needs to establish a robust vaccine monitoring and evaluation system to promptly identify and address issues related to vaccine efficacy and immunological persistence. The future trends and challenges in the development of polio vaccines will be one of the important issues in the field of medicine. China needs to strengthen international cooperation to jointly promote vaccine innovation and development in order to protect public health and safety. China should enhance collaboration between vaccine research institutions and manufacturing companies, improve supervision and guidance over vaccine production and distribution, and elevate the quality and safety of vaccines. Additionally, China also needs to intensify vaccine promotion and advocacy efforts, enhance public awareness and trust in vaccines, and increase vaccine coverage rates. With collective efforts in China, it is believed that future research and application of polio vaccines will achieve even more significant accomplishments and advancements, further safeguarding human health and well-being. Acknowledgments We would like to express our gratitude to Ms. Mengting Luo for her invaluable support throughout the entire process of creating this study, enabling us to gain a deeper understanding of the development and current status of polio vaccines. We would also like to extend our thanks to the research grant provided by the Cuixi Biotechnology Research Institute. Conflict of Interest Disclosure The authors affirm that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References Chen S.Y., Li Y., Yang S.Q., and Ying X.X., 2021, Advances in researches of serotype 2 novel oral polio vaccine, Chinese Journal of Preventive Medicine, (3): 413-417. Kew O.M., Sutter R.W., de Gourville E.M., Dowdle W.R., and Pallansch M.A., 2005, Vaccine-derived polioviruses and the endgame strategy for global polio eradication, Annu. Rev. Microbiol., 59: 587-635. https://doi.org/10.1146/annurev.micro.58.030603.123625 PMid:16153180 Modlin J.F., Bandyopadhyay A.S., and Sutter R., 2021, Immunization against poliomyelitis and the challenges to worldwide poliomyelitis eradication, J. Infect. Dis., 224(Supplement_4): S398-S404. https://doi.org/10.1093/infdis/jiaa622 PMid:34590135 PMCid:PMC8482017 Mohamed A., Akbar I.E., Chaudhury S., Wadood M.Z., Ather F., Jorba J., and Martinez M., 2022, Progress toward poliomyelitis Eradication-Afghanistan, January 2021-September 2022, Morb. Mortal. Wkly. Rep., 71(49): 1541-1546. https://doi.org/10.15585/mmwr.mm7149a1 PMid:36480464 PMCid:PMC9762895 Nathanson N., and Kew O.M., 2010, From emergence to eradication: the epidemiology of poliomyelitis deconstructed, Am. J. Epidemiol., 72(11): 1213-1229. https://doi.org/10.1093/aje/kwq320 PMid:20978089 PMCid:PMC2991634 Orenstein W.A., and Ahmed R., 2017, Simply put: vaccination saves lives, Proc Natl Acad. Sci. U.S.A., 114(16): 4031-4033. https://doi.org/10.1073/pnas.1704507114 PMid:28396427 PMCid:PMC5402432 Paul Y., and Priya A., 2004, Polio eradication in India: some observations, Vaccine, 22(31-32): 4144-4148. https://doi.org/10.1016/j.vaccine.2004.04.032 PMid:15532129 Platt L.R., Estívariz C.F., and Sutter R.W., 2014, Vaccine-associated paralytic poliomyelitis: a review of the epidemiology and estimation of the global burden, J. Infect. Dis., 210(Suppl 1): S380-389. https://doi.org/10.1093/infdis/jiu184 PMid:25316859 PMCid:PMC10424844 Su Y.Y., Zhao R.R., and Li C.G., 2021, Progress in research on poliovirus vaccine, Chinese Journal of Biologicals, (12): 1506-1510.
RkJQdWJsaXNoZXIy MjQ4ODYzNQ==