IJMMS_2025v15n4

International Journal of Molecular Medical Science, 2025, Vol.15, No.4, 185-194 http://medscipublisher.com/index.php/ijmms 192 Anagnostis P., Bosdou J., Kenanidis E., Potoupnis M., Tsiridis E., and Goulis D., 2020, Vitamin D supplementation and fracture risk: evidence for a U-shaped effect, Maturitas, 141: 63-70. https://doi.org/10.1016/j.maturitas.2020.06.016 Balduzzi S., Rücker G., and Schwarzer G., 2019, How to perform a meta-analysis with R: a practical tutorial, Evidence-Based Mental Health, 22: 153-160. https://doi.org/10.1136/ebmental-2019-300117 Bischoff-Ferrari H., Willett W., Orav E., Lips P., Meunier P., Lyons R., Flicker L., Wark J., Jackson R., Cauley J., Meyer H., Pfeifer M., Sanders K., Stähelin H., Theiler R., and Dawson-Hughes B., 2012, A pooled analysis of vitamin D dose requirements for fracture prevention, The New England Journal of Medicine, 367(1): 40-49. https://doi.org/10.1056/NEJMoa1109617 Bolland M., Grey A., and Avenell A., 2018, Effects of vitamin D supplementation on musculoskeletal health: a systematic review meta-analysis and trial sequential analysis, The Lancet, Diabetes and Endocrinology, 6(11): 847-858. https://doi.org/10.1016/S2213-8587(18)30265-1 Boonen S., Bischoff-Ferrari H., Cooper C., Lips P., Ljunggren Ö., Meunier P., and Reginster J., 2006, Addressing the musculoskeletal components of fracture risk with calcium and vitamin D: a review of the evidence, Calcified Tissue International, 78: 257-270. https://doi.org/10.1007/s00223-005-0009-8 Boonen S., Lips P., Bouillon R., Bischoff-Ferrari H., Vanderschueren D., and Haentjens P., 2007, Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials, The Journal of Clinical Endocrinology and Metabolism, 92(4): 1415-1423. https://doi.org/10.1210/JC.2006-1404 Bouillon R., LeBoff M., and Neale R., 2023, Health effects of vitamin D supplementation: lessons learned from randomized controlled trials and mendelian randomization studies, Journal of Bone and Mineral Research, 38(10): 1391-1403. https://doi.org/10.1002/jbmr.4888 Bouillon R., Manousaki D., Rosen C., Trajanoska K., Rivadeneira F., and Richards J., 2021, The health effects of vitamin D supplementation: evidence from human studies, Nature Reviews, Endocrinology, 18: 96-110. https://doi.org/10.1038/s41574-021-00593-z Cai W.P., Huang Z.M., Han Q.X., and Huang Y.L., 2025, Research on the chronic disease management model for the elderly based on a community health assessment system, International Journal of Clinical Case Reports, 15(1): 44-51. https://doi.org/10.5376/ijccr.2025.15.0005 Chakhtoura M., Bacha D., Gharios C., Ajjour S., Assaad M., Jabbour Y., Kahale F., Bassatne A., Antoun S., Akl E., Bouillon R., Lips P., Ebeling P., and Fuleihan G., 2021, Vitamin D supplementation and fractures in adults: a systematic umbrella review of meta-analyses of controlled trials, The Journal of Clinical Endocrinology and Metabolism, 107: 882-898. https://doi.org/10.1210/clinem/dgab742 Chapuy M., Arlot M., Duboeuf F., Brun J., Crouzet B., Arnaud S., Delmas P., and Meunier P., 1992, Vitamin D3 and calcium to prevent hip fractures in elderly women, The New England Journal of Medicine, 327(23): 1637-1642. https://doi.org/10.1097/00006254-199305000-00026 Cheung M., and Vijayakumar R., 2016, A guide to conducting a meta-analysis, Neuropsychology Review, 26: 121-128. https://doi.org/10.1007/s11065-016-9319-z Chung M., Lee J., Terasawa T., Lau J., and Trikalinos T., 2011, Vitamin D with or without calcium supplementation for prevention of cancer and fractures: an updated meta-analysis for the U.S. preventive services task force, Annals of Internal Medicine, 155: 827-838. https://doi.org/10.7326/0003-4819-155-12-201112200-00005 Cianferotti L., Bifolco G., Caffarelli C., Mazziotti G., Migliaccio S., Napoli N., Ruggiero C., and Cipriani C., 2024, Nutrition vitamin D and calcium in elderly patients before and after a hip fracture and their impact on the musculoskeletal system: a narrative review, Nutrients, 16(11): 1773. https://doi.org/10.3390/nu16111773 De Souza M.M., Dantas R., Durães V., Defante M., and Mendes T., 2024a, Vitamin D supplementation and the incidence of fractures in the elderly healthy population: a meta-analysis of randomized controlled trials, Journal of General Internal Medicine, 39(14): 2829-2836. https://doi.org/10.1007/s11606-024-08933-1 De Souza M., Dantas R., Duraes V., Renganathan G., and Mendes T., 2024b, 8224 Vitamin D supplementation for healthy elderly people and the incidence of fracture: a systematic review and meta-analysis, Journal of the Endocrine Society, 8(Supplement_1): bvae163-535. https://doi.org/10.1210/jendso/bvae163.535 Demay M.B., Pittas A.G., Bikle D.D., Diab D.L., Kiely M., Lazaretti-Castro M., Lips P., Mitchell D., Murad M., Powers S., Rao S., Scragg R., Tayek J., Valent A., Walsh J., and McCartney C., 2024, Vitamin D for the prevention of disease: an endocrine society clinical practice guideline, The Journal of Clinical Endocrinology and Metabolism, 109(8): 1907-1947. https://doi.org/10.1210/clinem/dgae290 Feige J., Moser T., Bieler L., Schwenker K., Hauer L., and Sellner J., 2020, Vitamin D supplementation in multiple sclerosis: a critical analysis of potentials and threats, Nutrients, 12(3): 783. https://doi.org/10.3390/nu12030783 Field A., and Gillett R., 2010, How to do a meta-analysis, The British Journal of Mathematical and Statistical Psychology, 63(Pt 3): 665-694. https://doi.org/10.1348/000711010X502733

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