International Journal of Molecular Medical Science, 2025, Vol.15, No.2, 54-68 http://medscipublisher.com/index.php/ijmms 58 Table 1 Basic characteristics of the 13 studies included Author (Year) Country Type of study Object of Study Data sources Predicted outcomes Sample size Sharathkumar et al. (2012) America Retrospective Study Child Patient, ≤Age 20 Two tertiary care pediatric hospitals VTE 519 Yen et al. (2016) America Retrospective Study Child Patient with Trauma, ≤Age 21 John Hopkins Preliminary Adult and Child Trauma Center VTE 17366 Cairo et al. (2018) America Retrospective Study Child Operation Patient, ≤Age 18 NSQIP-P Database VTE 218432 Marquez et al. (2016) America Prospective Cohort Study Child Patient with Severe Disease, <Age 18 Three Children’s Hospital located in the northeast of America DVT 175 Kerris et al. (2020) America Retrospective Study Child Patient with Severe Heart Disease, ≤Age 18 Tertiary care referral to the Children's Hospital cardiac ICU VTE 2204 Jaffray et al. (2021) America Retrospective Study Child Patient, ≤Age 21 Children's Hospital-Acquired Thrombosis Registry VTE 1567 Kerlin et al. (2015) America Retrospective Study Child Patient, ≤Age 18 Monocentric VTE 389 Papillon et al. (2023) America Retrospective Study Child Patient with Trauma, ≤Age 18 Trauma Quality Improvement Program(TQIP)Database VTE 347576 Spavor et al. (2016) Canada Retrospective Study Child Cancer Patient, ≤Age 18 Multi-center Study DVT 218 Walker et al. (2021) America Retrospective Study Child Patient, ≤Age 21 Little Monroe-Carrier Children's Society Hospital VTE 111352 Jaffray et al. (2022) America Retrospective Study Child Patient with Severe Disease, ≤Age 21 Multi-institutional Children's School Hospital-Acquired Thrombosis Registry VTE 735 Connelly et al. (2016) America Retrospective Study Child Patient with Trauma, ≤Age 21 National Trauma Database VTE 536423 Tiratrakoonseree et al. (2024) America Retrospective Study Child Patient, ≤Age 20 Two tertiary care pediatric hospitals VTE 519 Note: VTE stands for Venous Thromboembolism; DVT stands for Deep Vein Thrombosis; PE stands for Pulmonary Embolism
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