International Journal of Molecular Medical Science, 2025, Vol.15, No.2, 80-88 http://medscipublisher.com/index.php/ijmms 87 Chen L.C., Fan Z.Y., Wang H.Y., Wen D.C., and Zhang S.Y., 2019, Effect of polysaccharides from adlay seed on anti-diabetic and gut microbiota, Food & Function, 10(7): 4372-4380. https://doi.org/10.1039/C9FO00406H Cheng Z., Hu M., Tao J., Yang H., Yan P., An G., and Wang H., 2019, The protective effects of Chinese yam polysaccharide against obesity-induced insulin resistance, Journal of Functional Foods, 55: 238-247. https://doi.org/10.1016/j.jff.2019.02.023 Feng X., Zhang Q., Li J., Bie N., Li C., Lian R., Qin L., Feng Y., and Wang C., 2022, The impact of a novel Chinese yam-derived polysaccharide on blood glucose control in HFD and STZ-induced diabetic C57BL/6 mice, Food & Function, 13(5): 2681-2692. https://doi.org/10.1039/D1FO03830C He L.Y., Li Y., Niu S.Q., Bai J., Liu S.J., and Guo J.L., 2023, Polysaccharides from natural resource: ameliorate type 2 diabetes mellitus via regulation of oxidative stress network, Frontiers in Pharmacology, 14: 1184572. https://doi.org/10.3389/fphar.2023.1184572 van Herpt T.T., Ligthart S., Leening M., Hoek M., Lieverse A., Ikram M., Sijbrands E., Dehghan A., and Kavousi M., 2020, Lifetime risk to progress from pre-diabetes to type 2 diabetes among women and men: comparison between American Diabetes Association and World Health Organization diagnostic criteria, BMJ Open Diabetes Research and Care, 8(2): e001529. https://doi.org/10.1136/bmjdrc-2020-001529 Huang R., Xie J., Yu Y., and Shen M., 2020, Recent progress in the research of yam mucilage polysaccharides: isolation, structure and bioactivities, International Journal of Biological Macromolecules, 155: 1262-1269. https://doi.org/10.1016/j.ijbiomac.2019.11.095 Jiang Y.U., Zhou M.N., and Lu Q.J., 2015, Effects of yam polysaccharides on P-selectin expression and macrophage infiltration in diabetic nephropathy model rats, Clinical and Experimental Medical Sciences, 3(1): 11-21. https://doi.org/10.12988/cems.2015.521 Le B., Anh P.T.N., and Yang S.H., 2021, Polysaccharide derived from Nelumbo nucifera lotus plumule shows potential prebiotic activity and ameliorates insulin resistance in HepG2 cells, Polymers, 13(11): 1780. https://doi.org/10.3390/polym13111780 Li Q., Li W., Gao Q., and Zou Y., 2017, Hypoglycemic effect of Chinese yam (Dioscorea opposita rhizoma) polysaccharide in different structure and molecular weight, Journal of Food Science, 82(10): 2487-2494. https://doi.org/10.1111/1750-3841.13919 Li Z., Xiao W., Xie J., Chen Y., Yu Q., Zhang W., and Shen M., 2022, Isolation, characterization and antioxidant activity of yam polysaccharides, Foods, 11(6): 800. https://doi.org/10.3390/foods11060800 Liu X.X., Yan Y.Y., Liu H.M., Wang X.D., and Qin G.Y., 2019, Emulsifying and structural properties of polysaccharides extracted from Chinese yam by an enzyme-assisted method, LWT, 111: 242-251. https://doi.org/10.1016/j.lwt.2019.05.016 Mainous A.G., Tanner R.J., Baker R., Zayas C.E., and Harle C.A., 2014, Prevalence of prediabetes in England from 2003 to 2011: population-based, cross-sectional study, BMJ Open, 4(6): e005002. https://doi.org/10.1136/bmjopen-2014-005002 Ouyang J., Wang F., Li W., Li Q., and Su X., 2021, Structure characterization of polysaccharide from Chinese yam (Dioscorea opposite Thunb.) and its growth-promoting effects on streptococcus thermophilus, Foods, 10(11): 2698. https://doi.org/10.3390/foods10112698 Qiao Z., Du X., Zhuang W., Yang S., Li H., Sun J., Chen J., and Wang C., 2020, Schisandra chinensis acidic polysaccharide improves the insulin resistance in type 2 diabetic rats by inhibiting inflammation, Journal of Medicinal Food, 23(4): 358-366. https://doi.org/10.1089/jmf.2019.4469 Wang L., Zhang B., Xiao J., Huang Q., Li C., and Fu X., 2018, Physicochemical, functional, and biological properties of water-soluble polysaccharides from Rosa roxburghii Tratt fruit, Food Chemistry, 249: 127-135. https://doi.org/10.1016/j.foodchem.2018.01.011 Wang X., Huo X.Z., Liu Z., Yang R., and Zeng H.J., 2020, Investigations on the anti-aging activity of polysaccharides from Chinese yam and their regulation on klotho gene expression in mice, Journal of Molecular Structure, 1208: 127895. https://doi.org/10.1016/j.molstruc.2020.127895 Xiao M., Jia X., Wang N., Kang J., Hu X., Goff H., Cui S., Ding H., and Guo Q., 2024, Therapeutic potential of non-starch polysaccharides on type 2 diabetes: from hypoglycemic mechanism to clinical trials, Critical Reviews in Food Science and Nutrition, 64(4): 1177-1210. https://doi.org/10.1080/10408398.2022.2113366 Xu N., Zhou Y., Lu X., and Chang Y., 2021, Auricularia auricula‐judae (Bull.) polysaccharides improve type 2 diabetes in HFD/STZ‐induced mice by regulating the AKT/AMPK signaling pathways and the gut microbiota, Journal of Food Science, 86(12): 5479-5494. https://doi.org/10.1111/1750-3841.15963 Xue H.Y., Li J., Liu Y., Gao Q., Wang X., Zhang J., Tanokura M., and Xue Y.L., 2019, Optimization of the ultrafiltration-assisted extraction of Chinese yam polysaccharide using response surface methodology and its biological activity, International Journal of Biological Macromolecules, 121: 1186-1193. https://doi.org/10.1016/j.ijbiomac.2018.10.126
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