International Journal of Molecular Medical Science, 2025, Vol.15, No.2, 69-79 http://medscipublisher.com/index.php/ijmms 75 important for the development of health foods and nutritional supplements, and their application value in the prevention and control of chronic diseases is increasingly prominent (Santini et al., 2017). 7.3 Integrated application of multi-omics technologies Cross-omics technologies such as genomics and proteomics have revolutionized the research methods of food and medicine homologous substances. Metabolomics technology can effectively identify active substances and analyze their action pathways by tracking changes in food metabolites, providing a key basis for the research and development of functional foods. Although this technology still needs improvement in terms of detection stability and result reproducibility, its application prospects in the field of chronic disease prevention and treatment are broad (Hu et al., 2022). The systematic pharmacological approach has become an effective means to explore the therapeutic potential of plant active substances by establishing component-target networks (Noor et al., 2022). 7.4 Innovative application of intelligent analysis technology Data mining and intelligent analysis tools have significantly enhanced the screening efficiency of active ingredients. Researchers use machine learning methods (such as random forest models) to construct effect prediction systems, which can quickly identify potential active substances. This system can not only predict the effect of new compounds, but also shorten the drug research and development cycle (Tian et al., 2023). Multi-dimensional data analysis technology can identify the patterns that are difficult to capture by traditional means and significantly improve the accuracy of target molecule discrimination (Thomford et al., 2018). The application of digital simulation tools has deepened the research and development process of natural product drugs, highlighting the breakthrough value of intelligent technology in the development of innovative drugs (Thomford et al., 2018). 8 Future development trends and research directions 8.1 In-depth research on active ingredients Exploring the key components in dual-purpose food and medicine substances is the core to revealing their therapeutic mechanisms. Current research often uses intelligent models to identify and evaluate the activities of these molecules. For instance, the researchers established a database covering 503 kinds of FMH substances and over 27 000 molecules, and constructed predictive models for the inhibitory activities targeting the anti-inflammatory targets COX-2 and mPGES-1. This model has screened out a variety of potential inhibitors, laying the foundation for subsequent research and development (Tian et al., 2023). In terms of individual components of traditional Chinese medicine, flavonoids and saponins have performed particularly prominently in liver protection research (Zhang et al., 2018). Taking food and medicine resources such as kudzu root as examples, their core active components and action pathways have been analyzed and have shown extensive value in disease prevention and treatment (Zeng et al., 2022). 8.2 In-depth analysis of pharmacological mechanisms Clarifying the drug action mechanism of FMH substances is of great significance for their clinical application. Existing research has found that food components may affect the intestinal metabolic enzyme system and alter the process of drug action in the body. This suggests the need for a systematic study of the functional characteristics of bioactive components (Won et al., 2012). Systematic pharmacological methods are widely used in traditional medical research and are conducive to revealing the essence of the multi-target synergistic effect of FMH substances (Sun et al., 2023). The new strategy for analyzing the synergistic effect provides a new perspective for interpreting the combined effect of trace components in traditional Chinese medicine. This method is also applicable to the study of FMH substances (Shan et al., 2021). 8.3 Global health value of dual-purpose substances for food and medicine FMH substances, which have both food and drug properties, have significant advantages in the global health field. Relevant studies have shown that some traditional medicinal materials can combat viral infections by directly inhibiting viral activity and regulating immunity, etc. (Chen and Ye, 2022). Anti-aging components in natural products have also attracted much attention. In particular, compounds with the function of eliminating free radicals have outstanding potential in the research and development of anti-aging products (He et al., 2023).
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