IJMMS_2025v15n1

International Journal of Molecular Medical Science, 2025, Vol.15, No.1, 33-41 http://medscipublisher.com/index.php/ijmms 41 Masyuk T., Masyuk A., and LaRusso N., 2018, Polycystic liver disease: the interplay of genes causative for hepatic and renal cystogenesis, Hepatology, 67(6): 2462-2464. https://doi.org/10.1002/hep.29708 Masyuk T., Masyuk A., Pisarello M., Howard B., Huang B., Lee P., Fung X., Sergienko E., Ardecky R., Chung T., Pinkerton A.B., and LaRusso N.F., 2017, TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling, Hepatology, 66(4): 1197-1218. https://doi.org/10.1002/hep.29284 Miura S., Niida Y., Hashizume C., Fujii A., Takagaki Y., Kusama K., Akazawa S., Minami T., Mukai T., Furuichi K., Tsuchishima M., Ueda N., Takamura H., Koya D., and Ito T., 2022, Novel PKD2 missense mutation p.ile424ser in an individual with multiple hepatic cysts: a case report, Medicines, 9(4): 25. https://doi.org/10.3390/medicines9040025 Porath B., Gainullin V., Gall C., Dillinger E., Heyer C., Hopp K., Edwards M., Madsen C., Mauritz S., Banks C., Baheti S., Reddy B., Herrero J., Banales J., Hogan M., Tasic V., Watnick T., Chapman A., Vigneau C., Lavainne F., Audrézet M., Férec C., Meur L., Torres V., and Harris P., 2016, Mutations in GANAB, encoding the glucosidase iiα subunit, cause autosomal-dominant polycystic kidney and liver disease, American Journal of Human Genetics, 98(6): 1193-1207. https://doi.org/10.1016/j.ajhg.2016.05.004 Santos-Laso A., Izquierdo-Sánchez L., Lee-Law P.Y., Perugorria M.J., Marzioni M., Marin J.J.G., Bujanda L., and Banales J.M., 2017, New advances in polycystic liver diseases, Seminars in Liver Disease, 37: 45-55. https://doi.org/10.1055/s-0036-1597817 Savige J., Mallett A., Tunnicliffe D., and Rangan G., 2015, KHA-CARI Autosomal dominant polycystic kidney disease guideline: management of polycystic liver disease, Seminars in Nephrology, 35(6): 618-622. Spirli C., Mariotti V., Villani A., Fabris L., Fiorotto R., and Strazzabosco M., 2017, Adenylyl cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in polycystic liver disease, Journal of Hepatology, 66(3): 571–580. https://doi.org/10.1016/j.jhep.2016.10.032 van Aerts R.M.M., van de Laarschot L.F.M., Banales J.M., and Drenth J.P.H., 2018, Clinical management of polycystic liver disease, J. Hepatol., 68(4):827-837. https://doi.org/10.1053/j.gastro.2018.09.025 van de Laarschot L.F.M., and Drenth J.P.H., 2017, Genetics and mechanisms of hepatic cystogenesis, Biochimica et Biophysica Acta: Molecular Basis of Disease, 1864: 1491–1497. https://doi.org/10.1016/j.bbadis.2017.08.003 Wang J., Yang H., Guo R., Sang X., and Mao Y., 2020, Association of a novel PKHD1 mutation in a family with autosomal dominant polycystic liver disease, Annals of Translational Medicine, 9(2): 120. https://doi.org/10.21037/ATM-20-3318 Wills E.S., Cnossen W.R., Veltman J.A., Woestenenk R., Steehouwer M., Salomon J., Te Morsche R.H., Huch M., Hehir-Kwa J.Y., Banning M.J., Pfundt R., Roepman R., Hoischen A., and Drenth J.P., 2016, Chromosomal abnormalities in hepatic cysts point to novel polycystic liver disease genes, European Journal of Human Genetics, 24(12): 1707-1714. https://doi.org/10.1038/ejhg.2016.97 Yu Z., Shen, X., Hu, C., Zeng, J., Wang, A., and Chen, J., 2022, Molecular mechanisms of isolated polycystic liver diseases, Frontiers in Genetics, 13. https://doi.org/10.3389/fgene.2022.846877

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