International Journal of Molecular Medical Science, 2024, Vol.14, No.5, 315-323 http://medscipublisher.com/index.php/ijmms 315 Feature Review Open Access Modern Therapies with Rehmannia glutinosa: Integrating Traditional Chinese and Contemporary Medicine YanLou Physicov Med. Tech. Ltd., Zhuji, 311800, Zhejiang, China Corresponding email: yan.lou@pmtcl.org International Journal of Molecular Medical Science, 2024, Vol.14, No.5 doi: 10.5376/ijmms.2024.14.0032 Received: 05 Sep., 2024 Accepted: 12 Sep., 2024 Published: 24 Oct., 2024 Copyright © 2024 Lou, This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Preferred citation for this article: Lou Y., 2024, Modern therapies with Rehmannia glutinosa: integrating traditional chinese and contemporary medicine, International Journal of Molecular Medical Science, 14(5): 315-323 (doi: 10.5376/ijmms.2024.14.0032) Abstract Rehmannia glutinosa, a fundamental herb in Traditional Chinese Medicine (TCM), has been used for centuries to treat a variety of ailments, including anemia, diabetes, and osteoporosis. This study explores the integration of traditional uses of Rehmannia glutinosa with contemporary medical approaches to enhance therapeutic outcomes. Recent research has revealed that the bioactive compounds in Rehmannia glutinosa, such as catalpol and rehmanniosides, exhibit significant pharmacological effects, including anti-inflammatory, antioxidant, and neuroprotective properties. This study analyzed traditional applications and modern scientific research findings, highlighting the potential of Rehmannia glutinosa in treating chronic diseases and promoting overall health. By bridging the gap between TCM and contemporary medicine, this study aims to provide a comprehensive understanding of the therapeutic benefits of Rehmannia glutinosa, paving the way for innovative treatment strategies that leverage the strengths of both medical paradigms. Keywords Rehmannia glutinosa; Traditional Chinese Medicine; Contemporary medicine; Bioactive compounds; Integrative therapy 1 Introduction PRehmannia glutinosa, a crucial herb in Traditional Chinese Medicine (TCM), is highly esteemed for its diverse therapeutic properties. Integrating TCM with contemporary medical practices opens new avenues for fully utilizing the potential of traditional herbs like Rehmannia glutinosa. This study aims to explore modern therapies involving Rehmannia glutinosa, highlighting its integration into contemporary medicine. Rehmannia glutinosa, belonging to the family Scrophulariaceae, is widely used in TCM to nourish Yin and invigorate the kidneys. It contains over 70 compounds, including iridoids, saccharides, and amino acids, which exhibit significant pharmacological actions on the blood, immune, endocrine, cardiovascular, and nervous systems (Zhang et al., 2008). Modern studies have identified its potential in managing conditions such as diabetes, hypertension, and neurodegenerative diseases, further solidifying its role in contemporary therapeutic practices (Hsu et al., 2014). This study provides a comprehensive overview of the therapeutic applications of Rehmannia glutinosa in both TCM and modern medicine. As a traditional herb, Rehmannia glutinosa boasts a rich history and wide application; its specific usage and efficacy in various medical systems need systematic review and summary. Furthermore, an in-depth analysis of the pharmacological mechanisms of Rehmannia glutinosa is conducted to reveal the scientific basis of its effectiveness. By studying the chemical composition and pharmacological actions of Rehmannia glutinosa, we can better understand its mechanisms in different therapeutic fields, thereby providing theoretical support for its application in modern medicine. Additionally, the integration of Rehmannia glutinosa into contemporary medical treatments and its potential for new drug development are evaluated. With the rise of integrated traditional and Western medicine treatments, the application prospects of Rehmannia glutinosa in modern medicine are broad. This study will explore its application cases in modern clinical practice, analyze its potential drug development value, and propose future research directions.
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