IJMMS_2024v14n4

International Journal of Molecular Medical Science, 2024, Vol.14, No.4, 252-263 http://medscipublisher.com/index.php/ijmms 263 Rohn T., Kim N., Isho N., and Mack J., 2018, The potential of CRISPR/Cas9 gene editing as a treatment strategy for alzheimer's disease, Journal of Alzheimer's Disease and Parkinsonism, 8: 1000439. https://doi.org/10.4172/2161-0460.1000439 PMid:30090689 PMCid:PMC6078432 Rudenko Y., and Sholomon S., 2023, Prospects of using gene therapy and nanotechnologies for the treatment of neurodegenerative diseases, Ukrainian Neurological Journal, 2023: 45. https://doi.org/10.30978/UNJ2023-1-4-45 Shellhaas R., deVeber G., Bonkowsky J., Augustine E., Bassuk A., Calame D., Carrasco M., Dlamini N., Felling R., Glass H., Grinspan Z., Guerriero R., Hewitt A., Jeste S., Knowles J., Lyons-Warren A., Maricich S., Musolino P., Raju G., Rho J., Rotenberg A., Sherr E., Soul J., and Ziobro J., 2021, Gene-targeted therapies in pediatric neurology: challenges and opportunities in diagnosis and delivery, Pediatric Neurology, 125: 53-57. https://doi.org/10.1016/j.pediatrneurol.2021.09.011 Shim K., Kang S., An S., and Kang M., 2022, Identification of the third case of PSEN1 Tyr389His variant in early-onset alzheimer's disease in Korea, International Journal of Molecular Sciences, 23(24): 16192. https://doi.org/10.3390/ijms232416192 PMid:36555832 PMCid:PMC9781446 Sudhakar V., and Richardson R., 2018, Gene therapy for neurodegenerative diseases, Neurotherapeutics, 16: 166-175. https://doi.org/10.1007/s13311-018-00694-0 PMid:30542906 PMCid:PMC6361055 Sun J., Carlson-Stevermer J., Das U., Shen M., Delenclos M., Snead A., Wang L., Loi J., Petersen A., Stockton M., Bhattacharyya A., Jones M., Sproul A., McLean P., Zhao X., Saha K., and Roy S., 2018, A CRISPR/Cas9 based strategy to manipulate the Alzheimer's amyloid pathway, bioRxiv, 28: 310193. https://doi.org/10.1101/310193 Tedeschi D., Cunha A., Cominetti M., and Pedroso R., 2021, Efficacy of gene therapy to restore cognition in Alzheimer's disease: a systematic review, Current Gene Therapy, 21(3): 246-257. https://doi.org/10.2174/1566523221666210120091146 Triaca V., Sposato V., Bolasco G., Ciotti M., Pelicci P., Bruni A., Cupidi C., Maletta R., Feligioni M., Nisticò R., Canu N., and Calissano P., 2016, NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease, Aging Cell, 15: 661-672. https://doi.org/10.1111/acel.12473 PMid:27076121 PMCid:PMC4933663 Tuszynski M., Yang J., Barba D., U H., Bakay R., Pay M., Masliah E., Conner J., Kobalka P., Roy S., and Nagahara A., 2015, Nerve growth factor gene therapy: activation of neuronal responses in Alzheimer disease, JAMA Neurology, 72(10): 1139-1147. https://doi.org/10.1001/jamaneurol.2015.1807 PMid:26302439 PMCid:PMC4944824 Unnisa A., Greig N., and Kamal M., 2023, Nanotechnology-based gene therapy as a credible tool in the treatment of Alzheimer's disease, Neural Regeneration Research, 18: 2127-2133. https://doi.org/10.4103/1673-5374.369096 PMid:37056119 PMCid:PMC10328264 Weber-Adrian D., 2019, Gene therapy: a strategy for the treatment of Alzheimer's disease, Health Science Inquiry, 6(1):23. https://doi.org/10.29173/hsi190 Yiannopoulou K., Anastasiou A., Zachariou V., and Pelidou S., 2019, Reasons for failed trials of disease-modifying treatments for alzheimer disease and their contribution in recent research, Biomedicines, 7(4): 97. https://doi.org/10.3390/biomedicines7040097 Zhang J., 2024, From genomic data to personalized medical decisions: challenges and opportunities, International Journal of Clinical Case Reports, 14(2): 107-116. https://doi.org/10.5376/ijccr.2024.14.0013 Zhou H., Gong Y., Liu Y., Huang A., Zhu X., Liu J., Yuan G., Zhang L., Wei J., and Liu J., 2020, Intelligently thermoresponsive flower-like hollow nano-ruthenium system for sustained release of nerve growth factor to inhibit hyperphosphorylation of tau and neuronal damage for the treatment of Alzheimer's disease, Biomaterials, 237: 119822. https://doi.org/10.1016/j.biomaterials.2020.119822

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