International Journal of Molecular Medical Science, 2024, Vol.14, No.2, 100-105 http://medscipublisher.com/index.php/ijmms 103 Figure 3 EVs from body fluids expose PS at varying levels 2 Insight of Research Findings Extracellular vesicles (EVs) enriched with phosphatidylserine (PS) significantly reduce viral attachment by competing with viruses for cellular receptors. There are variations in the PS content of EVs from different sources. Data charts illustrate the effectiveness of PS-enriched extracellular vesicles and liposomes in preventing viral infections. 3 Evaluation of the Research This study validates the theory of extracellular vesicles (EVs) as an innate antiviral mechanism. Experiments have shown that EVs exposing more phosphatidylserine (PS) are most effective at blocking viruses that utilize apoptotic mimicry mechanisms. Additionally, the research also demonstrates the differences in antiviral activity among various types of vesicles and liposomes. 4 Concluding Remarks The conclusion drawn from the research is that extracellular vesicles (EVs) exposing phosphatidylserine (PS) as a defense mechanism in body fluids may be a potentially effective means of combating specific viruses. Synthetic liposomes that mimic this mechanism have the potential to be used in developing new antiviral therapies.
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