International Journal of Molecular Medical Science, 2024, Vol.14, No.2, 132-143 http://medscipublisher.com/index.php/ijmms 141 Acknowledgments The author sincere thanks to the two anonymous peer reviewers for their valuable feedback on the manuscript. Conflict of Interest Disclosure The author affirms that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References Arif M., Sadayappan S., Becker R.C., Martin L.J., and Urbina E.M., 2019, Epigenetic modification: a regulatory mechanism in essential hypertension, Hypertension Research, 42(8): 1099-1113. https://doi.org/10.1038/s41440-019-0248-0 PMid:30867575 Berillo O., Huo K.G., Fraulob-Aquino J.C., Richer C., Briet M., Boutouyrie P., Lipman M.L., Sinnett D., Paradis P., and Schiffrin E.L., 2020, Circulating let-7g-5p and miR-191-5p are independent predictors of chronic kidney disease in hypertensive patients, American Journal of Hypertension, 33(6): 505-513. https://doi.org/10.1093/ajh/hpaa031 PMid:32115655 PMCid:PMC7241936 Bhargava A., Khare K.N., Bunkar N., Chaudhury K., Pandey C.K., Jain K.S., and Mishra K.P., 2017, Cell-free circulating epigenomic signatures: non-invasive biomarker for cardiovascular and other age-related chronic diseases, Current Pharmaceutical Design, 23(8): 1175-1187. https://doi.org/10.2174/1381612822666161027145359 PMid:27817745 Bielecka-Dabrowa A., Gluba-Brzózka A., Michalska-Kasiczak M., Misztal M., Rysz J., and Banach M., 2015, The multi-biomarker approach for heart failure in patients with hypertension, International Journal of Molecular Sciences, 16(5): 10715-10733. https://doi.org/10.3390/ijms160510715 PMid:25984599 PMCid:PMC4463672 Cardona-Monzonís A., Beltrán-García J., Ibañez-Cabellos J.S., Pérez-Machado G., Malkani K., Sanchis-Gomar, F., Mena-Mollá S., and García-Giménez J.L., 2018, Epigenetic biomarkers in cardiovascular disease, Journal of Laboratory and Precision Medicine, 3(3). https://doi.org/10.21037/jlpm.2018.02.04 Cui J.J., Wang L.Y., Tan Z.R., Zhou H.H., Zhan X., and Yin J.Y., 2020, Mass spectrometry‐based personalized drug therapy, Mass Spectrometry Reviews, 39(5-6): 523-552. https://doi.org/10.1002/mas.21620 PMid:31904155 Das S., Reddy M.A., and Natarajan R., 2020, Role of epigenetic mechanisms regulated by enhancers and long noncoding RNAs in cardiovascular disease, Current Opinion in Cardiology, 35(3): 234-241. https://doi.org/10.1097/HCO.0000000000000728 PMid:32205477 PMCid:PMC7526644 de la Rocha C., Zaina S., and Lund G., 2020, Is any cardiovascular disease-specific DNA methylation biomarker within reach?, Current Atherosclerosis Reports, 22: 1-9. https://doi.org/10.1007/s11883-020-00875-3 PMid:32844297 Eirin A., Lerman A., and Lerman L.O., 2014, Mitochondrial injury and dysfunction in hypertension-induced cardiac damage, European Heart Journal, 35(46): 3258-3266. https://doi.org/10.1093/eurheartj/ehu436 PMid:25385092 PMCid:PMC4258226 Friso S., Carvajal C.A., Fardella C.E., and Olivieri O., 2015, Epigenetics and arterial hypertension: the challenge of emerging evidence, Translational Research, 165(1): 154-165. https://doi.org/10.1016/j.trsl.2014.06.007 PMid:25035152 García-Giménez J.L., Seco-Cervera M., Tollefsbol T.O., Romá-Mateo C., Peiró-Chova L., Lapunzina P., and Pallardó F.V., 2017, Epigenetic biomarkers: current strategies and future challenges for their use in the clinical laboratory, Critical Reviews in Clinical Laboratory Sciences, 54(7-8): 529-550. https://doi.org/10.1080/10408363.2017.1410520 PMid:29226748 PMCid:PMC6733278 Giannakoulas G., Mouratoglou S.A., Gatzoulis M.A., and Karvounis H., 2014, Blood biomarkers and their potential role in pulmonary arterial hypertension associated with congenital heart disease. a systematic review, International Journal of Cardiology, 174(3): 618-623. https://doi.org/10.1016/j.ijcard.2014.04.156 PMid:24814894 Gonzalez-Jaramillo V., Portilla-Fernandez E., Glisic M., Voortman T., Bramer W., Chowdhury R., A.J.M. Roks, Jan Danser A.H., Muka T., Nano J., and Franco O.H., 2019, The role of DNA methylation and histone modifications in blood pressure: a systematic review, Journal of Human Hypertension, 33(10): 703-715. https://doi.org/10.1038/s41371-019-0218-7 PMid:31346255
RkJQdWJsaXNoZXIy MjQ4ODYzNQ==