International Journal of Clinical Case Reports, 2025, Vol.15, No.5, 219-227 http://medscipublisher.com/index.php/ijccr 225 6.3 Multi-center, multi-method, long-term tracking To address these deficiencies, future research should conduct surveys in more locations and include elderly groups from different regions and care environments. This can enhance the universality of the research results and facilitate cross-cultural comparisons, thereby enabling a more comprehensive understanding of the actual impact of isolation on the health of the elderly (Sterina et al., 2021). In addition, adopting a combination of qualitative and quantitative methods-including objective health indicators, standardized scales and long-term follow-up-can enhance the reliability of data and simultaneously reflect both short-term and long-term effects. Especially longitudinal studies are of great significance for understanding the changes in health behaviors and the continuous impact on quality of life after the end of isolation (Cohen et al., 2020; Mendoza-Ruvalcaba et al., 2022). 7 Concluding Remarks The home isolation during the COVID-19 pandemic has brought about significant changes in the health and quality of life of elderly patients. Most people's reduced physical activity, increased sedentary time and disrupted daily habits all lead to a decline in physical and mental health, such as increased depression, anxiety and feelings of loneliness. However, some elderly people have demonstrated strong emotional adaptability and coping abilities. Compared with young people, their sense of happiness remains stable, and in some cases, it has even increased. Based on these results, it is necessary to formulate public health policies as soon as possible to address the multi-faceted impacts of isolation on the physical and mental health of the elderly. Specific measures can include encouraging the elderly to exercise safely at home, providing necessary psychological assistance, and using technological means to maintain social interaction. Targeted intervention methods need to be adopted to reduce the negative impacts brought by isolation and meet the diverse needs of the elderly in public health emergencies. Future health programs should integrate multiple approaches and take into account individual differences, such as developing telemedicine, arranging planned family exercises and providing special social support, to help the elderly maintain or improve their health and quality of life during and after isolation. At the same time, it is necessary to promote long-term and multi-regional follow-up research, continuously improve relevant measures, ensure that they are simple, feasible, effective, and can solve various special problems that the elderly may encounter in future public health crises. Acknowledgments The authors extend sincere thanks to two anonymous peer reviewers for their feedback on the manuscript. Conflict of Interest Disclosure The authors affirm that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References Alves G., Casali M., Veras A., Carrilho C., Costa E., Rodrigues V., and Dourado M., 2020, A systematic review of home-setting psychoeducation interventions for behavioral changes in dementia: some lessons for the COVID-19 pandemic and post-pandemic assistance, Frontiers in Psychiatry, 11: 577871. https://doi.org/10.3389/fpsyt.2020.577871 Cagnin A., Di Lorenzo R., Marra C., Bonanni L., Cupidi C., Laganà V., Rubino E., Vacca A., Provero P., Isella V., Vanacore N., Agosta F., Appollonio I., Caffarra P., Pettenuzzo I., Sambati R., Quaranta D., Guglielmi V., Logroscino G., Filippi M., Tedeschi G., Ferrarese C., Rainero I., and Bruni A., 2020, Behavioral and psychological effects of coronavirus disease-19 quarantine in patients with dementia, Frontiers in Psychiatry, 11: 578015. https://doi.org/10.3389/fpsyt.2020.578015 Cheng S., and Zhang F., 2021, Benefit-finding buffers the effects of quarantine on older adults’ mental health during the COVID-19 pandemic, Innovation in Aging, 5: 717. https://doi.org/10.1093/geroni/igab046.2679 Cohen G., Russo M., Campos J., and Allegri R., 2020, COVID-19 epidemic in argentina: worsening of behavioral symptoms in elderly subjects with dementia living in the community, Frontiers in Psychiatry, 11: 866. https://doi.org/10.3389/fpsyt.2020.00866 Cai W.P., Huang Z.M., Han Q.X., and Huang Y.L., 2025, Research on the chronic disease management model for the elderly based on a community health assessment system, International Journal of Clinical Case Reports 15(1): 44-51.
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