International Journal of Clinical Case Reports, 2025, Vol.15, No.1, 24-33 http://medscipublisher.com/index.php/ijccr 25 2 Chemical Composition Analysis of Hangbai Chrysanthemum Essential Oil 2.1 Major components: terpenes and aromatic compounds The essential oil of Hangbai Chrysanthemum, a variety of Chrysanthemum morifolium, is rich in terpenes and aromatic compounds. A study utilizing Gas Chromatography-Mass Spectrometry (GC-MS) identified a significant number of compounds in the essential oil, with terpenes such as juniper camphor and alpha-curcumene being prominent (Guan et al., 2007; Guo et al., 2008). These terpenes are known for their aromatic properties and potential therapeutic benefits, contributing to the oil's medicinal applications. In addition to terpenes, the essential oil contains various aromatic compounds that enhance its fragrance and therapeutic potential. Compounds like borneol and benzyl benzoate are notable for their aromatic qualities and are commonly found in essential oils used for medicinal purposes (Zhu et al., 2005; Guo et al., 2008). The presence of these compounds underscores the potential of Hangbai Chrysanthemum essential oil in aromatherapy and other medicinal applications. 2.2 Seasonal variation and geographical factors affecting chemical composition The chemical composition of Hangbai Chrysanthemum essential oil is influenced by seasonal variations and geographical factors. Studies have shown that the concentration of certain compounds, such as juniper camphor, can vary significantly depending on the time of harvest and the specific growing conditions of the region (Guo et al., 2008). These variations can affect the quality and efficacy of the essential oil, making it crucial to consider these factors in its production and application. Geographical factors, including soil type and climate, It not only determines the origin of Chrysanthemum morifolium as a traditional Chinese medicine (Figure 1)，also play a critical role in determining the chemical profile of the essential oil. Different cultivars of Chrysanthemum morifolium grown in various regions exhibit distinct chemical compositions, as evidenced by the differences in the number and concentration of compounds identified in oils from different habitats (Guan et al., 2007; Guo et al., 2008). Understanding these variations is essential for standardizing the quality of Hangbai Chrysanthemum essential oil for medicinal use. Figure 1 production and processing base of Chrysanthemum morifoliumin Tongxiang Image caption: a: Hangzhou white chrysanthemum production base; b: Hangzhou White Chrysanthemum processing base 2.3 Methods for studying the bioactivity of essential oil components To study the bioactivity of Hangbai Chrysanthemum essential oil components, researchers employ various analytical techniques. GC-MS is a primary method used to identify and quantify the chemical constituents of the oil, providing insights into its potential bioactive properties (Guan et al., 2007; Guo et al., 2008). This technique allows for the detailed analysis of the oil's complex mixture of compounds, facilitating the identification of those with significant therapeutic potential. In addition to chemical analysis, bioassays are conducted to evaluate the biological activity of the essential oil components. These assays help determine the efficacy of the oil in various medicinal applications, such as antimicrobial or anti-inflammatory effects. By combining chemical analysis with bioactivity studies, researchers can better understand the therapeutic potential of Hangbai Chrysanthemum essential oil and its components (Guo et al., 2008).
RkJQdWJsaXNoZXIy MjQ4ODYzNA==