International Journal of Clinical Case Reports 2024, Vol.14, No.6, 312-326 http://medscipublisher.com/index.php/ijccr cardiovascular protection by improving lipid profiles, reducing oxidative stress, and alleviating inflammation (Zhao et al., 2018; Zhang et al., 2015; Zheng et al., 2022). Clinical trials are necessary to confirm these benefits in human populations. Preliminary data indicate that the consumption of X. sorbifolia oil could lead to improved cardiovascular health outcomes, particularly in individuals with hyperlipidemia or at high risk of atherosclerosis. The oil's antioxidant and anti-inflammatory properties may also offer protective effects against other oxidative stress-related conditions, such as hypertension and diabetes, which are closely linked to cardiovascular health (Zhang et al., 2015; Chen et al., 2021). Xanthoceras sorbifolia oil holds significant potential for cardiovascular protection due to its rich composition of beneficial fatty acids, antioxidants, and anti-inflammatory compounds. Further research, including well-designed clinical trials, is essential to fully elucidate its therapeutic potential and establish its role in the prevention and management of cardiovascular diseases. 6 Applications of Xanthoceras SorbifoliaOil in Other Health Areas 6.1 Neuroprotective effects of Xanthoceras Sorbifolia oil Xanthoceras sorbifolia oil has shown significant potential in neuroprotection, particularly in the context of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). The oil contains various bioactive compounds, including triterpenoids and phenolic acids, which contribute to its neuroprotective properties. Studies have demonstrated that specific compounds isolated from X. sorbifolia, such as barrigenol-type triterpenoids, exhibit protective effects against oxidative stress and inflammation in neuronal cells. For instance, the compound XS-8 was found to significantly improve learning and memory impairments in mice models of AD by enhancing hippocampal oxidative defense and reducing pro-inflammatory cytokines (Li et al., 2020). Additionally, total triterpenoid saponins from X. sorbifolia (TSX) have been shown to improve cognitive functions in AD models by mitigating oxidative stress and synaptic damage (Ji et al., 2017). Moreover, nervonic acid, a component of X. sorbifolia oil, has been studied for its effects on PD. It was found to reduce oxidative stress and inflammation in PD models, suggesting its potential as a therapeutic agent for neurodegenerative diseases (Figure 3) (Hu et al., 2023). These findings highlight the promise of X. sorbifolia oil in neuroprotection and its potential application in treating neurodegenerative conditions 319 . Figure 3 Cellular inflammatory reaction (Adopted from Hu et al., 2023) Image caption: (A) Comparison of inflammatory factor levels in SH-5Y5Y. (B) Comparison of inflammatory factor levels in PC-12. *: Compared with the control group, there is a difference p 0.05. #: Compared with the model group, there is a difference p 0.05. &:
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