IJCCR_2024v14n2

International Journal of Clinical Case Reports 2024, Vol.14, No.2, 107-116 http://medscipublisher.com/index.php/ijccr 115 The future of personalized medicine is filled with challenges and opportunities. Through efforts in technological advancement, policy making, education, training, and international cooperation, we can expect to see the widespread adoption and optimization of personalized medicine in the near future, thus providing more precise and efficient treatment options for patients. Reference Alyass A., Turcotte M., and Meyre D., 2015, From big data analysis to personalized medicine for all: challenges and opportunities, BMC Med Genomics 8: 33. https://doi.org/10.1186/s12920-015-0108-y André F., Bachelot T., Commo F., Campone M., Arnedos M., Diéras V., Lacroix-Triki M., Lacroix L., Cohen P., Gentien D., Adélaide J., Dalenc F., Gonçalves A., Lévy C., Ferrero J., Bonneterre J., Lefeuvre C., Jimenez M., Filleron T., and Bonnefoi H., 2014, Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (safir01/unicanCER), The Lancet. Oncology, 15(3): 267-274. https://doi.org/10.1016/S1470-2045(13)70611-9 Assimes T., and Roberts R., 2016, Genetics: implications for prevention and management of coronary artery disease, Journal of the American College of Cardiology, 68(25): 2797-2818. https://doi.org/10.1016/j.jacc.2016.10.039 Borodinov A., Manoilov V., Zarutsky I., Petrov A., and Kurochkin V., 2020, GEnerations of dna sequencing methods (Review), 30: 3-20. https://doi.org/10.18358/np-30-4-i320 Cheval J., Sauvage V., Frangeul L., Dacheux L., Guigon G., Dumey N., Pariente K., Rousseaux C., Dorange F., Berthet N., Brisse S., Moszer I., Bourhy H., Manuguerra C., Lecuit M., Burguière A., Caro V., and Eloit M., 2011, Evaluation of high-throughput sequencing for identifying known and unknown viruses in biological samples, Journal of Clinical Microbiology, 49: 3268-3275. https://doi.org/10.1128/JCM.00850-11 Chong H.Y., Allotey P.A., and Chaiyakunapruk N., 2018, Current landscape of personalized medicine adoption and implementation in Southeast Asia, BMC Med Genomics, 11: 94. https://doi.org/10.1186/s12920-018-0420-4 Collins F., 1999, The Human genome project and the future of medicine, Annals of the New York Academy of Sciences, 882. https://doi.org/10.1111/j.1749-6632.1999.tb08532.x International human genome sequencing consortium, 2001, Initial sequencing and analysis of the human genome, Nature, 409: 860-921. Delpierre C., and Lefèvre T., 2023, Precision and personalized medicine: What their current definition says and silences about the model of health they promote, Implication for the development of personalized health, Front. Sociol, 8: 1112159. https://doi.org/10.3389/fsoc.2023.1112159 Hartin S., Means J., Alaimo J., and Younger S., 2020, Expediting rare disease diagnosis: a call to bridge the gap between clinical and functional genomics, Molecular Medicine, 26.117 https://doi.org/10.1186/s10020-020-00244-5 Hekel R., Budiš J., Kucharík M., Radvánszky J., Pös Z., and Szemeš T., 2021, Privacy-preserving storage of sequenced genomic data, BMC Genomics, 22: 712. https://doi.org/10.1186/s12864-021-07996-2 Kim H., Jeon S., Kim C., Kim Y., Cho Y., Kim J., Blazyte A., Manica A., Lee S., and Bhak J., 2019, Chromosome-scale assembly comparison of the korean reference genome koref from promethion and pacbio with hi-c mapping information, GigaScience, 8. https://doi.org/10.1093/gigascience/giz125 Liu C., Cai L., Zhong D., and Wang J., 2016, The Correlation of PKIG and its role in the tumor microenvironment, Chinese Journal of Lung Cancer, 19: 38-45. Liu Q., Li H., Li B., Ren M., Li Z., Chen Y., Zheng Z., Meng Y., and Feng H., 2023, The Correlation of PKIG and its role in the tumor microenvironment, Chinese Journal of Lung Cancer, 26: 523-537. Loman N., Misra R., Dallman T., Constantinidou C., Gharbia S., Wain J., and Pallen M., 2012, Performance comparison of benchtop high-throughput sequencing platforms. Nature Biotechnology, 30: 434-439. https://doi.org/10.1038/nbt.2198 Metzker M., 2010, Sequencing technologies - the next generation, Nat Rev Genet, 11: 31-46 https://doi.org/10.1038/nrg2626 Posey J., 2019, Genome sequencing and implications for rare disorders, Orphanet Journal of Rare Diseases, 14: 153. https://doi.org/10.1186/s13023-019-1127-0 Quattrocchi A., Fante Z., Fazio N., Romano S., Volonnino G., Fazio V., Santoro P., and Gennaro U., 2019, Personalized medicine in psychiatric disorders: prevention and bioethical questions, La Clinica terapeutica, 170(6): 421-424. Rasmussen I., and Frikke-Schmidt R., 2023, Modifiable cardiovascular risk factors and genetics for targeted prevention of dementia, European Heart Journal, 44: 2526-2543. https://doi.org/10.1093/eurheartj/ehad293

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