International Journal of Clinical Case Reports 2024, Vol.14, No.1, 14-22 http://medscipublisher.com/index.php/ijccr 18 the specific organs and meridians that drugs act on. According to TCM theory, different drugs correspond to different organs and meridians, leading to distinct therapeutic effects. Drug toxicity indicates the harmful effects a drug may have on the body at a certain dosage. Some drugs may cause damage to the human body when the dosage exceeds a certain range. Therefore, it is crucial to pay attention to dosage and usage methods when using these drugs to avoid toxic side effects. The meaning and function of drug properties are crucial in TCM, determining the selection and application of Chinese medicinal herbs in treating diseases. TCM practitioners, based on the drug properties and factors such as the patient's constitution and condition, rationally combine drugs to achieve the therapeutic goals of regulating yin and yang, balancing organs, and restoring health. Additionally, understanding the toxicity and side effects of drugs helps Chinese medicine practitioners avoid adverse reactions, ensuring the safety and effectiveness of the treatment. Therefore, the study and application of drug properties are of significant importance for the development and clinical practice of TCM. 2.2 Historical background and development of meridian tropism theory The theory of meridian tropism is one of the significant concept in TCM, referring to the impact of drugs on the meridians of the human body. The historical background and development of meridian tropism theory can be traced back to the ancient origins and formation of TCM. In ancient China, the development of medicine underwent continuous practice and summarization, and early medical theories were primarily derived from clinical experience. With the development of medicine, there was an increasing focus on establishing connections between drugs and the meridians of the human body, leading to the formulation of meridian tropism theory. The origins of meridian tropism theory can be found in ancient medical classics such as the Huángdì Nèijīng (the Yellow Emperor's Inner Canon) and the Nánjīng (Classic of Questioning), where a systematic summary of the application of drugs based on their impact on the meridians was presented. During the Han Dynasty, Zhang Zhongjing's Shānghán Zábìng Lùn (Treatise on Cold Damage and Miscellaneous Diseases) became a significant milestone in the history of TCM. In this book, he provided detailed records on the properties, effects, and meridian tropism of various drugs, laying a solid foundation for the development of the meridian tropism theory. Afterwards, the theory of meridian tropism gradually became one of the important theories in TCM, and was further developed and improved during the Sui and Tang Dynasties. During the Sui and Tang Dynasties, Sun Simiao's work Qiānjīn Yàofāng (Important Prescriptions Worth a Thousand Gold for Emergency) further enriched the content of the meridian tropism theory. He provided more detailed explanations of the properties, effects, and meridian tropism of drugs in the book. Sun Simiao introduced important concepts such as "cold-heat deficiency-excess" and categorized drugs according to the meridians associated with the five organs and six viscera. This contribution provided valuable references for later physicians in clinical applications. In the Song Dynasty, the book Běncǎo Yǎnyì (Augmented Materia Medica) conducted a more in-depth study of the meridian tropism and application of drugs. Additionally, medical practitioners in the Song Dynasty integrated the theory of meridian tropism with the studies of meridians and pulses, forming a more comprehensive system of TCM theory. During the Ming and Qing Dynasties, with the spread of medical education and the accumulation of clinical practice, the theory of meridian tropism underwent further refinement and development. Běncǎo Gāngmù (Compendium of Materia Medica) provided detailed organization and summarization of the meridian tropism and application of drugs, making a significant contribution to the inheritance and development of the theory of meridian tropism. The theory of Channel Tropism, as one of the crucial theories in TCM, has undergone a long process of historical development, continually enriching and refining over time. Presently, the theory of Channel Tropism continues to
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