CGE_2025v13n6

Cancer Genetics and Epigenetics, 2025, Vol.13, No.6, 287-299 http://medscipublisher.com/index.php/cge 298 Henriksen T., Demuth C., Frydendahl A., Nors J., Nesic M., Rasmussen M., Reinert T., Larsen O., Jaensch C., Løve U., Andersen P., Kolbro T., Thorlacius-Ussing O., Monti A., Gögenur M., Kildsig J., Bondeven P., Schlesinger N., Iversen L., Gotschalck K., and Andersen C., 2023, Unraveling the potential clinical utility of circulating tumor DNA detection in colorectal cancer-evaluation in a nationwide Danish cohort, Annals of Oncology, 35(2): 229-239. https://doi.org/10.1016/j.annonc.2023.11.009 Hisamatsu Y., Ando K., Kudo K., Nakanishi R., Kawazoe T., Zaitsu Y., Kusumoto T., Hata T., Kagawa Y., Yoshizumi T., Ashida N., Niiro H., Hirose T., and Oki E., 2025, A 14-Gene panel for predicting colorectal cancer recurrence using circulating tumor DNA in different testing conditions, Cancer Science, 116(9): 2499-2506. https://doi.org/10.1111/cas.70114 Huang F., Wei R., Mei S., Xiao T., Zhao W., Zheng Z., and Liu Q., 2025, Clinical calculator based on clinicopathological characteristics predicts local recurrence and overall survival following radical resection of stage II-III colorectal cancer, Frontiers in Oncology, 15: 1494255. https://doi.org/10.3389/fonc.2025.1494255 Hwang S., Shin S., Kim Y., and Lee J., 2025, Risk factors for recurrence in stage I colorectal cancer after curative resection: a systematic review and meta-analysis, Annals of Surgical Treatment and Research, 108: 39-48. https://doi.org/10.4174/astr.2025.108.1.39 Imaoka K., Shimomura M., Okuda H., Yano T., Shimizu W., Yoshimitsu M., Ikeda S., Nakahara M., Kohyama M., Kobayashi H., Shimizu Y., Kochi M., Akabane S., Sumitani D., Mukai S., Takakura Y., Ishizaki Y., Kodama S., Fujimori M., Ishikawa S., Adachi T., Hattori M., and Ohdan H., 2025, Intraoperative blood loss predicts local recurrence after curative resection for stage I–III colorectal cancer, World Journal of Surgery, 49: 1172-1182. Kagawa Y., Taniguchi H., Kotani D., Hashimoto T., Bando H., Hamaguchi T., Kanazawa A., Kato T., Ando K., Yasui H., Shinozaki E., Sunakawa Y., Takashima A., Yamazaki K., Yuki S., Nakamura Y., Wakabayashi M., Nakajima H., Ohta T., and Yoshino T., 2025, Longitudinal ctDNA monitoring and prediction of anti-EGFR rechallenge outcomes in RAS/BRAF wild-type metastatic colorectal cancer (mCRC): the REMARRY and PURSUIT trials, Journal of Clinical Oncology, 43(16_suppl): 3514. https://doi.org/10.1200/jco.2025.43.16_suppl.3514 Kalil J., Krzywoń L., Petrillo S., Tsamchoe M., Zlotnik O., Lazaris A., and Metrakos P., 2024, Feasibility of ctDNA in detecting minimal residual disease and predicting recurrence for colorectal cancer liver metastases, Frontiers in Oncology, 14: 1418696. https://doi.org/10.3389/fonc.2024.1418696 Kasai S., Hatakeyama K., Shiomi A., Kagawa H., Manabe S., Yamaoka Y., Tanaka Y., Igaki T., and Yamaguchi K., 2025, Risk factors for relapse based on the molecular profiling of Japanese patients with stage II colorectal cancer, Journal of Clinical Oncology, 43(4_suppl): 215. https://doi.org/10.1200/jco.2025.43.4_suppl.215 Kawashima M., Yamada T., Miyasaka T., Kanaka S., Kuriyama S., Uehara K., Matsuda A., Ohta R., Sonoda H., Taniai N., and Yoshida H., 2025, Impact of minimal residual disease on early recurrence of liver metastatic colorectal cancer, Cancer Science, 116: 1366-1374. https://doi.org/10.1111/cas.16442 Kim S., Lee J., Kim S., Kim J., Hong Y., and Kim T., 2025, Prognostic relevance of ctDNA RAS mutation in patients with metastatic colorectal cancer treated with cetuximab, Clinical Colorectal Cancer, 24(3): 341-351. https://doi.org/10.1016/j.clcc.2025.03.002 Kotani D., Oki E., Nakamura Y., Yukami H., Mishima S., Bando H., Shirasu H., Yamazaki K., Watanabe J., Kotaka M., Hirata K., Akazawa N., Kataoka K., Sharma S., Aushev V., Aleshin A., Misumi T., Taniguchi H., Takemasa I., Kato T., Mori M., and Yoshino T., 2023, Molecular residual disease and efficacy of adjuvant chemotherapy in patients with colorectal cancer., Nature Medicine, 29: 127-134. Massaro G., Venturini J., Rossini D., Vannini A., Brugia M., Lavacchi D., Conticello C., Valle I., Ravizza D., Pillozzi S., and Antonuzzo L., 2025, Beneath the surface of Colorectal Cancer: unmasking the evolving nature of (Neo)RAS, Critical Reviews in Oncology/Hematology, 211: 104746. https://doi.org/10.1016/j.critrevonc.2025.104746 Mo S., Ye L., Wang D., Han L., Zhou S., Wang H., Dai W., Wang Y., Luo W., Wang R., Xu Y., Cai S., Liu R., Wang Z., and Cai G., 2023, Early detection of molecular residual disease and risk stratification for stage I to III colorectal cancer via circulating tumor DNA methylation, JAMA Oncology, 9(6): 770-778. Nakamura Y., Watanabe J., Akazawa N., Hirata K., Kataoka K., Yokota M., Kato K., Kotaka M., Kagawa Y., Yeh K., Mishima S., Yukami H., Ando K., Miyo M., Misumi T., Yamazaki K., Ebi H., Okita K., Hamabe A., Sokuoka H., Kobayashi S., Laliotis G., Aushev V., Sharma S., Jurdi A., Liu M., Aleshin A., Rabinowitz M., Bando H., Taniguchi H., Takemasa I., Kato T., Kotani D., Mori M., Yoshino T., and Oki E., 2024, ctDNA-based molecular residual disease and survival in resectable colorectal cancer, Nature Medicine, 30: 3272-3283. https://doi.org/10.1038/s41591-024-03254-6 Negro S., Pulvirenti A., Trento C., Indraccolo S., Ferrari S., Scarpa M., Urso E., Bergamo F., Pucciarelli S., Deidda S., Restivo A., Lonardi S., and Spolverato G., 2025, Circulating tumor DNA as a real-time biomarker for minimal residual disease and recurrence prediction in stage II colorectal cancer: a systematic review and meta-analysis, International Journal of Molecular Sciences, 26(6): 2486. Ryu H., Kim J., Park Y., Cho E., Choo J., Kim J., Baek S., and Kwak J., 2023, Recurrence patterns and risk factors after curative resection for colorectal cancer: insights for postoperative surveillance strategies, Cancers, 15(24): 5791. https://doi.org/10.3390/cancers15245791 Shim H., Heo S., Sun J., Choi M., Park S., Hong C., Kim S., Park S., Kong S., and Baek J., 2025, Clinical utility of monitoring circulating tumor DNA using a targeted next-generation sequencing panel in patients with colorectal cancer, Annals of Laboratory Medicine, 45: 450-458. https://doi.org/10.3343/alm.2024.0598

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