Cancer Genetics and Epigenetics, 2025, Vol.13, No.5, 224-235 http://medscipublisher.com/index.php/cge 225 2 The Concept and Development of Digital Health Intervention 2.1 Definition and classification: mobile applications, remote monitoring, hybrid mode In digital health tools (DHIs), various technologies are used to help people develop healthy habits, improve their health conditions, and also provide telemedicine services. Common methods include: mobile applications that can provide health knowledge, record physical discomfort symptoms and daily activities; The remote monitoring system can collect and transmit patients' health data for a long time. The combination of online care and offline diagnosis and treatment forms a hybrid model. Mobile applications are mainly used to help people manage their own health, such as setting medication reminders or communicating with medical staff. Remote monitoring relies on tools such as wearable devices and physiological sensors to timely understand physical indicators and disease changes through remote platforms (Jat and Grønli, 2024). This hybrid approach combines the advantages of digital healthcare and traditional healthcare. With the assistance of technology and face-to-face consultation, patients can cooperate with treatment more actively, enhance the trust relationship between doctors and patients, and better cope with complex demands (Zakaria et al., 2024; Liu and Zhang, 2025). According to the way DHIs is used and the degree of its integration with medical processes, it can be further classified in detail. For instance, some are application-oriented and emphasize self-management by patients. Some are platform-centered, supporting multi-disciplinary collaboration and nursing coordination. Overall, more effective approaches often combine multiple methods, such as simultaneously integrating applications, remote monitoring and remote consultation, to provide more comprehensive, patient-centered services (Da Silva et al., 2025). 2.2 Global development trends Globally, the research and application of DHIs are accelerating continuously, and the related clinical trials and practical applications in the treatment of chronic diseases and cancer have significantly increased. In recent years, several randomized controlled trials have evaluated the role of mobile applications, remote monitoring and hybrid models in improving treatment outcomes, medication compliance and satisfaction (Abodawood et al., 2024; Hausvater et al., 2024). Whether relying on advanced equipment in high-income countries or using mobile technology to make up for insufficient resources in low - and middle-income regions, these intervention measures have been promoted in different medical Settings (Chigurupati, 2023; Baka et al., 2025). Research progress has initially demonstrated the feasibility and acceptance of DHIs, and there are data indicating its potential in enhancing patient engagement, reducing rehospitalization rates, and improving clinical outcomes. However, there are still problems such as uneven research levels, insufficient long-term data, and unequal opportunities and capabilities to use digital technologies. The current research focuses include optimizing intervention programs, promoting the integration of DHIs with health information systems, and evaluating their cost-effectiveness and promotion value (Da Silva et al., 2025). 2.3 Driving factors The increasing use of smart phones, tablets and wearable devices is the main reason for the rapid development of digital health tools (DHIs). With these devices, data can be collected in a timely manner, personalized suggestions can be given, and remote communication can also be conducted, thereby helping to promote and expand the scope of digital healthcare (Farai et al., 2024; Zakaria et al., 2024). Meanwhile, the combination of digital health methods with electronic health records and information systems has also improved the usage effect, achieving smooth data exchange, medical cooperation and group health management (Mezzalira et al., 2024). Support in terms of policies and regulations is also very important. Many countries and international organizations (such as the World Health Organization's Global Digital Health Initiative) are promoting the construction, assessment and implementation of digital health, and also attach great importance to network coverage, data security and compliance with regulations. These practices, along with investments in digital infrastructure, reimbursement systems and interdisciplinary collaboration, have jointly driven innovation, enabling digital health interventions to be more widely used worldwide (Jat and Grønli, 2024; Da Silva et al., 2025).
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