Cancer Genetics and Epigenetics 2024, Vol.12, No.1, 66-69 http://www.medscipublisher.com/index.php/cge 67 Figure 2 Validation of predictors and prognostic value of CD8IE and FoxP3IS in cases from the QUASAR 2 trial Figure 4 displays the proportion of patients without recurrence across N0, N1, and N2 stages, categorized by different CD8IE-FoxP3IS density levels (high, medium, low). Multivariable analysis indicates that higher CD8IE-FoxP3IS densities are associated with improved prognosis across all N stages, particularly in the N0 high-density group, where the three-year recurrence-free interval reaches 94%. The pie charts show the importance of various factors in the multivariable regression, emphasizing the critical role of immune infiltration in adjusting tumor staging risks.
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