Medicinal Plant Research 2025, Vol.15, No.6, 283-290 http://hortherbpublisher.com/index.php/mpr 289 References Bakr A., Shao P., and Farag M., 2022, Recent advances in glycyrrhizin metabolism, health benefits, clinical effects and drug delivery systems for efficacy improvement; a comprehensive review, Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 99: 153999. https://doi.org/10.1016/j.phymed.2022.153999 Batiha G., Beshbishy A., El-Mleeh A., Abdel-Daim M., and Devkota H., 2020, Traditional uses, bioactive chemical constituents, and pharmacological and toxicological activities of Glycyrrhiza glabra L. (Fabaceae), Biomolecules, 10: 352. https://doi.org/10.3390/biom10030352 Bisht D., Rashid M., Arya R., Kumar D., Chaudhary S., Rana V., and Sethiya N., 2021, Revisiting liquorice (Glycyrrhiza glabra L.) as anti-inflammatory, antivirals and immunomodulators: Potential pharmacological applications with mechanistic insight, Phytomedicine Plus, 2: 100206. https://doi.org/10.1016/j.phyplu.2021.100206 Cheng B., Dong Y., Yu H., Wang Y., Liu Y., Liu C., and Wang L., 2025, Glycyrrhizic acid inhibited inflammatory response in LPS-stimulated microglial BV2 cells via MAPK, Akt and NF-κB signaling pathways, Die Pharmazie, 80(4): 55-59. https://doi.org/10.1691/ph.2025.5532 Cheng L., Huang C., Xiong X., Jiang J., Wang F., Zhang D., Liu S., Feng Y., Hu S., and Zhang H., 2023, Glabridin ameliorates DNFB induced atopic dermatitis by suppressing MAPK/NF κB signaling pathways in mice, Tropical Journal of Pharmaceutical Research, 22(3): 455-463. https://doi.org/10.4314/tjpr.v22i3.9 De Filippis G., Amalfitano D., Russo C., Tommasino C., and Rinaldi A., 2025, A systematic mapping study of semantic technologies in multi-omics data integration, Journal of Biomedical Informatics, 136: 104809. https://doi.org/10.1016/j.jbi.2025.104809 Frattaruolo L., Carullo G., Brindisi M., Mazzotta S., Bellissimo L., Rago V., Curcio R., Dolce V., Aiello F., and Cappello A., 2019, Antioxidant and anti-inflammatory activities of flavanones fromGlycyrrhiza glabra L. (licorice) leaf phytocomplexes: identification of licoflavanone as a modulator of NF-kB/MAPK pathway, Antioxidants, 8(6): 186. https://doi.org/10.3390/antiox8060186 Hasan M., Ara I., Mondal M., and Kabir Y., 2021, Phytochemistry, pharmacological activity, and potential health benefits of Glycyrrhiza glabra, Heliyon, 7: e07240. https://doi.org/10.1016/j.heliyon.2021.e07240 Huan C., Xu Y., Zhang W., Guo T., Pan H., and Gao S., 2021, Research Progress on the Antiviral Activity of Glycyrrhizin and its Derivatives in Liquorice, Frontiers in Pharmacology, 12: 680674. https://doi.org/10.3389/fphar.2021.680674 Husain I., Bala K., Khan I., and Khan S., 2021, A review on phytochemicals, pharmacological activities, drug interactions, and associated toxicities of licorice (Glycyrrhiza sp.), Food Frontiers, 2: 110. https://doi.org/10.1002/fft2.110 Ko H., Lee S., Jee W., Jung J., Kim K., Jung H., and Jang H., 2021, Gancaonin N from Glycyrrhiza uralensis Attenuates the Inflammatory Response by Downregulating the NF-κB/MAPK Pathway on an Acute Pneumonia In Vitro Model, Pharmaceutics, 13(10): 1028. https://doi.org/10.3390/pharmaceutics13071028 Li J., Xu D., Wang L., Zhang M., Zhang G., Li E., and He S., 2021, Glycyrrhizic acid inhibits SARS-CoV-2 infection by blocking spike protein-mediated cell attachment, Molecules, 26(20): 6090. https://doi.org/10.3390/molecules26206090 Li Y., Xia C., Luo M., Huang Y., Xia Z., Li Y., and Wang Y., 2025, Comparative genomics of three medicinal Glycyrrhiza species unveiled novel candidates for the production of important bioactive compounds, The Plant Journal, 122(4): e70223. https://doi.org/10.1111/tpj.70223 Liu F., Gu Z., Yi F., Liu X., Zou W., Xu Q., Yuan Y., Chen N., and Tang J., 2025, Potential of Glycyrrhiza in the prevention of colitis-associated colon cancer, Fitoterapia, 179: 106398. https://doi.org/10.1016/j.fitote.2025.106398 Lu J., Ye D., and Bai B., 2021, Constituents, Pharmacokinetics, and pharmacology of gegen-qinlian decoction, Frontiers in Pharmacology, 12: 668418. https://doi.org/10.3389/fphar.2021.668418 Lu Y., Ding Z., Zhang D., Zhu F., and Gao B., 2025, Integrated metabolomic and transcriptomic analysis reveals the pharmacological effects and differential mechanisms of isoflavone biosynthesis in four species of Glycyrrhiza, International Journal of Molecular Sciences, 26: 2539. https://doi.org/10.3390/ijms26062539 Pastorino G., Cornara L., Soares S., Rodrigues F., and Oliveira M., 2018, Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review, Phytotherapy Research, 32(12): 2323-2339. https://doi.org/10.1002/ptr.6178 Semenescu I., Avram Ș., Similie D., Minda D., Diaconeasa Z., Muntean D., Lazăr A., Gurgus D., and Danciu C., 2024, Phytochemical, antioxidant, antimicrobial and safety profile of Glycyrrhiza glabra L. extract obtained from romania, Plants, 13(23): 3265. https://doi.org/10.3390/plants13233265 Sharifi-Rad J., Quispe C., Herrera-Bravo J., Belén L., Kaur R., Kręgiel D., Uprety Y., Beyatli A., Yeskaliyeva B., Kirkin C., Özçelik B., Sen S., Acharya K., Sharopov F., Cruz-Martins N., Kumar M., Razis A., Sunusi U., Kamal R., Shaheen S., and Suleria H., 2021, Glycyrrhiza genus: enlightening phytochemical components for pharmacological and health-promoting abilities, Oxidative Medicine and Cellular Longevity, 2021: 7571132. https://doi.org/10.1155/2021/7571132
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