MPR_2025v15n4

Medicinal Plant Research 2025, Vol.15, No.4, 178-187 http://hortherbpublisher.com/index.php/mpr 187 Wang Y., Li X., Zhao P., Qu Z., Bai D., Gao X., Zhao C., Chen J., and Gao W., 2019, Physicochemical characterizations of polysaccharides from Angelica Sinensis Radix under different drying methods for various applications, International Journal of Biological Macromolecules, 121: 381-389. https://doi.org/10.1016/j.ijbiomac.2018.10.035 Xiao H., Wang Y., Wang Z., Wang B., Hu L., Hou J., Du K., Sun N., and Wang L., 2023, Angelica sinensis polysaccharides ameliorated 5-Fluorouracil-induced damage of early B cell progenitors by alleviating oxidative stress of IL-7 producing mesenchymal stem and progenitor cells, Biomedicine and Pharmacotherapy, 167: 115599. https://doi.org/10.1016/j.biopha.2023.115599 Xu Y., Zhu B. W., Sun R., Li X., Wu D., and Hu J.N., 2023, Colon-targeting Angelica sinensis polysaccharide nanoparticles with dual responsiveness for alleviation of ulcerative colitis, ACS Applied Materials and Interfaces, 15(22): 26298-26315. https://doi.org/10.1021/acsami.3c02128 Xue, Y., Zhou, S., Yang, Z., Hao, P., Wang, L., Cui, W., Liu, W., and Liu, R. (2023). Angelica sinensis polysaccharide inhibits inflammation of collagen-induced arthritis rat fibroblast-like synoviocytes by inhibiting JAK2/STAT3 and MAPK signaling. Arabian Journal of Chemistry, 16(12), 105320. https://doi.org/10.1016/j.arabjc.2023.105320 Ye J., Shen S., Dai X., and Zhang T., 2023, Angelica sinensis polysaccharide ameliorates myocardial ischemia-reperfusion injury in rats by inhibiting TLR4/NF-κB, Tropical Journal of Pharmaceutical Research, 22(4): 777-782. https://doi.org/10.4314/tjpr.v22i4.9 Zhang T., Liu W., Fu C., Qiao Y., Xiao K., Ren L., Feng C., Wang J., Yang W., Li X., and Cao W., 2021, Structures and anti-melanoma activities of two polysaccharides from Angelica sinensis (Oliv.) Diels, International Journal of Biological Macromolecules, 183: 972-981. https://doi.org/10.1016/j.ijbiomac.2021.05.021 Zhang Y., Cui Z., Mei H., Xu J., Zhou T., Cheng F., and Wang K., 2019, Angelica sinensis polysaccharide nanoparticles as a targeted drug delivery system for enhanced therapy of liver cancer, Carbohydrate Polymers, 219: 143-154. https://doi.org/10.1016/J.CARBPOL.2019.04.041 Zhao Y., Feng Y., Jing X., Liu Y., and Liu A., 2021, Structural characterization of an alkali-soluble polysaccharide from Angelica sinensis and its antitumor activity in vivo, Chemistry and Biodiversity, 18(6): e2100089. https://doi.org/10.1002/cbdv.202100089 Zhou Y., Guo X., Chen W., and Liu J., 2019, Angelica polysaccharide mitigates lipopolysaccharide-evoked inflammatory injury by regulating microRNA-10a in neuronal cell line HT22, Artificial Cells, Nanomedicine, and Biotechnology, 47(1): 3194-3201. https://doi.org/10.1080/21691401.2019.1614595 Zhuang C., Xu N., Gao G., Ni S., Miao K., Li C., Wang L., and Xie H., 2016, Polysaccharide from Angelica sinensis protects chondrocytes from H2O2-induced apoptosis through its antioxidant effects in vitro, International Journal of Biological Macromolecules, 87: 322-328. https://doi.org/10.1016/j.ijbiomac.2016.02.031 Zou Y., Li C., Fu Y., Jiang Q., Peng X., Li L., Song X., Zhao X., Li Y., Chen X., Feng B., Huang C., Jia R., Ye G., Tang H., and Yin Z., 2022, The comparison of preliminary structure and intestinal anti-inflammatory and anti-oxidative activities of polysaccharides from different root parts of Angelica sinensis (Oliv.) Diels, Journal of Ethnopharmacology, 295: 115446. https://doi.org/10.1016/j.jep.2022.115446 Zou Y., Li C., Fu Y., Ji Z.X., Zhao Y., Peng X., Wang J., Yin Z., Li Y., Song X., Li L., Zhao X., Feng B., Huang C., Ye G., Tang H., Chen J., Li R., Chen X., and Tian M., 2023, Angelica sinensis aboveground part polysaccharide and its metabolite 5-MT ameliorate colitis via modulating gut microbiota and TLR4/MyD88/NF-κB pathway, International Journal of Biological Macromolecules, 242: 124689. https://doi.org/10.1016/j.ijbiomac.2023.124689

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