MPR_2025v15n4

Medicinal Plant Research 2025, Vol.15, No.4, 169-177 http://hortherbpublisher.com/index.php/mpr 176 Iqbal H., Kim Y., Jin M., and Rhee D., 2024, Ginseng as a therapeutic target to alleviate gut and brain diseases via microbiome regulation, Journal of Ginseng Research, 49(1): 12-21. https://doi.org/10.1016/j.jgr.2024.04.005 Ji X., Hou C., Shi M., Yan Y., and Liu Y., 2020, An insight into the research concerning Panax ginseng C.A. Meyer polysaccharides: a review, Food Reviews International, 38(6): 1149-1165. https://doi.org/10.1080/87559129.2020.1771363 Kim D., 2017, Gut microbiota-mediated pharmacokinetics of ginseng saponins, Journal of Ginseng Research, 42(3): 255-263. https://doi.org/10.1016/j.jgr.2017.04.011 Liang W., Zhou K., Jian P., Chang Z., Zhang Q., Liu Y., Xiao S., and Zhang L., 2021, Ginsenosides improve nonalcoholic fatty liver disease via integrated regulation of gut microbiota, inflammation and energy homeostasis, Frontiers in Pharmacology, 12: 622841. https://doi.org/10.3389/fphar.2021.622841 Li S., Qi Y., Chen L., Qu D., Li Z., Gao K., Chen J., and Sun Y., 2019, Effects of Panax ginseng polysaccharides on the gut microbiota in mice with antibiotic-associated diarrhea, International Journal of Biological Macromolecules, 124: 931-937. https://doi.org/10.1016/j.ijbiomac.2018.11.271 Lin L., Tang R., Liu Y., Li Z., Li H., and Yang H., 2024, Research on the anti-aging mechanisms of Panax ginseng extract in mice: a gut microbiome and metabolomics approach, Frontiers in Pharmacology, 15: 1415844. https://doi.org/10.3389/fphar.2024.1415844 Park J., 2024, Metabolism and drug interactions of Korean ginseng based on the pharmacokinetic properties of ginsenosides: current status and future perspectives, Journal of Ginseng Research, 48(3): 253-265. https://doi.org/10.1016/j.jgr.2024.02.003 Peng M., Wang L., Su H., Zhang L., Yang Y., Sun L., Wu Y., Ran L., Liu S., Yin M., Li S., and Chunyu W., 2022, Ginsenoside Rg1 improved diabetes through regulating the intestinal microbiota in high-fat diet and streptozotocin-induced type 2 diabetes rats, Journal of Food Biochemistry, 46(8): e14321. https://doi.org/10.1111/jfbc.14321 Qu Q., Yang F., Zhao C., Liu X., Yang P., Li Z., Han L., and Shi X., 2020, Effects of fermented ginseng on the gut microbiota and immunity of rats with antibiotic-associated diarrhea, Journal of Ethnopharmacology, 259: 113594. https://doi.org/10.1016/j.jep.2020.113594 Ratan Z., Haidere M., Hong Y., Park S., Lee J., Lee J., and Cho J., 2020, Pharmacological potential of ginseng and its major component ginsenosides, Journal of Ginseng Research, 45(2): 199-210. https://doi.org/10.1016/j.jgr.2020.02.004 Ren T., Liu F., Wang D., Li B., Jiang P., Li J., Li H., Chen C., Wu W., and Jiao L., 2022, Rhamnogalacturonan-I enriched pectin from steamed ginseng ameliorates lipid metabolism in type 2 diabetic rats via gut microbiota and AMPK pathway, Journal of Ethnopharmacology, 292: 115862. https://doi.org/10.1016/j.jep.2022.115862 Seong E., Bose S., Han S., Song E., Lee M., Nam Y., and Kim H., 2021, Positive influence of gut microbiota on the effects of Korean red ginseng in metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial, EPMA Journal, 12(2): 177-197. https://doi.org/10.1007/s13167-021-00243-4 Song H., Lee J., Yi S., Kim W., Kim Y., Namgoong B., Choe A., Cho G., Shin J., Park Y., Kim M., and Cho S., 2023, Red ginseng dietary fiber shows prebiotic potential by modulating gut microbiota in dogs, Microbiology Spectrum, 11(5): e00949-23. https://doi.org/10.1128/spectrum.00949-23 Wang D., Shao S., Zhang Y., Zhao D., and Wang M., 2021, Insight into polysaccharides from Panax ginseng C. A. Meyer in improving intestinal inflammation: modulating intestinal microbiota and autophagy, Frontiers in Immunology, 12: 683911. https://doi.org/10.3389/fimmu.2021.683911 Wang L., Shao L., Huang S., Liu Z., Zhang W., Hu K., and Huang W., 2023, Metabolic characteristics of ginsenosides from Panax ginseng in rat feces mediated by gut microbiota, Journal of Pharmaceutical and Biomedical Analysis, 237: 115786. https://doi.org/10.1016/j.jpba.2023.115786 Won H., Kim H., Park T., Kim H., Jo K., Jeon H., Ha S., Hyun J., Jeong A., Kim J., Park Y., Eo Y., and Lee J., 2018, Non-clinical pharmacokinetic behavior of ginsenosides, Journal of Ginseng Research, 43(3): 354-360. https://doi.org/10.1016/j.jgr.2018.06.001 Wu Y., Liu S., Ren T., Luo L., Luo J., Zhang M., Li F., Dai Y., Zheng F., Pi Z., and Yue H., 2024, Ginseng fermentation solution affects the gut microbiota in zebrafish with alcoholic liver disease via PI3K/Akt pathway, Phytomedicine, 128: 155495. https://doi.org/10.1016/j.phymed.2024.155495 Zhang X., 2024, Breeding high-yield and disease-resistant carrot varieties using marker-assisted selection, International Journal of Horticulture, 14(4): 263-274. https://doi.org/10.5376/ijh.2024.14.0028 Zhang X., Khakisahneh S., Han S., Song E., Nam Y., and Kim H., 2024, Ginseng extracts improve circadian clock gene expression and reduce inflammation directly and indirectly through gut microbiota and PI3K signaling pathway, NPJ Biofilms and Microbiomes, 10: 39. https://doi.org/10.1038/s41522-024-00498-5

RkJQdWJsaXNoZXIy MjQ4ODYzNA==