MPR_2025v15n3

Medicinal Plant Research 2025, Vol.15, No.3, 142-150 http://hortherbpublisher.com/index.php/mpr 149 Chang D., Gao S., Zhou G., Deng S., Jia J., Wang E., and Cao W., 2021, The chromosome-level genome assembly of Astragalus sinicus and comparative genomic analyses provide new resources and insights for understanding legume-rhizobial interactions, Plant Communications, 3(3): 100263. https://doi.org/10.1016/j.xplc.2021.100263 Chen S., Sun W., Wu W., Chen W., Wang Y., Dong Y., Liu Y., Xu Z., Sun C., Yin Q., Li Y., Luo M., Xiao Y., and Wan H., 2020, Molecular genetics of medicinal plants, past achievement, and new era, China Journal of Chinese Materia Medica, 45(23): 5577-5588. https://doi.org/10.19540/j.cnki.cjcmm.20201016.601 Chen Y., Fang T., Su H., Duan S.R., Wang P., Wu L., Sun W., Hu Q., Zhao M., Sun L., and Dong X., 2022, A reference-grade genome assembly for Astragalus mongholicus and insights into the biosynthesis and high accumulation of triterpenoids and flavonoids in its roots, Plant Communications, 4(5): 100469. https://doi.org/10.1016/j.xplc.2022.100469 Dong X.J., 2024, Pharmacological effects of aromatic medicinal plants: comprehensive analysis of active ingredients and mechanisms of action, Medicinal Plant Research, 14(1): 11-30. https://doi.org/10.5376/mpr.2024.14.0002 Dong P., Wang L., Chen Y., Wang L., Liang W., Wang H., Cheng J., Chen Y., and Guo F., 2024, Germplasm resources and genetic breeding of Huang-Qi (Astragali Radix): a systematic review, Biology, 13(8): 625. https://doi.org/10.3390/biology13080625 Fan H., Chai Z., Yang X., Liu A., Sun H., Wu Z., Li Q.C., and Zhou R., 2024, Chromosome-scale genome assembly of Astragalus membranaceus using PacBio and Hi-C technologies, Scientific Data, 11: 38. https://doi.org/10.1038/s41597-024-03852-6 Hur M., Um Y., Lee Y., Lee Y., Koo S., Park W., Kim J., Huh Y., and Moon Y., 2021, Development of whole genome sequence-based novel SSR markers in Astragalus membranaceus (Fisch.), Korean Journal of Medicinal Crop Science, 29(6): 418-426. https://doi.org/10.7783/kjmcs.2021.29.6.418 Jayakodi M., Schreiber M., Stein N., and Mascher M., 2021, Building pan-genome infrastructures for crop plants and their use in association genetics, DNA Research, 28(1): dsaa030. https://doi.org/10.1093/dnares/dsaa030 Kang J., Hur M., Kim C., Yang S., and Lee S., 2024, Enhancing transcriptome analysis in medicinal plants: multiple unigene sets in Astragalus membranaceus, Frontiers in Plant Science, 15: 1301526. https://doi.org/10.3389/fpls.2024.1301526 Kloosterman A., Cimermancic P., Elsayed S., Du C., Hadjithomas M., Donia M., Fischbach M., Van Wezel G., and Medema M., 2020, Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides, PLoS Biology, 18(12): e3001026. https://doi.org/10.1371/journal.pbio.3001026 Lei W., Ni D., Wang Y., Shao J., Wang X., Yang D., Wang J., Chen H., and Liu C., 2016, Intraspecific and heteroplasmic variations, gene losses and inversions in the chloroplast genome of Astragalus membranaceus, Scientific Reports, 6: 21669. https://doi.org/10.1038/srep21669 Li J., Harata-Lee Y., Denton M., Feng Q., Rathjen J., Qu Z., and Adelson D., 2017, Long read reference genome-free reconstruction of a full-length transcriptome from Astragalus membranaceus reveals transcript variants involved in bioactive compound biosynthesis, Cell Discovery, 3: 17031. https://doi.org/10.1038/celldisc.2017.31 Li S., Hu X., Liu F., and Hu W., 2025, Bioactive components and clinical potential of Astragalus species, Frontiers in Pharmacology, 16: 1585697. https://doi.org/10.3389/fphar.2025.1585697 Li X., Mu Y., Hua M., Wang J., and Zhang X., 2024, Integrated phenotypic, transcriptomics and metabolomics: growth status and metabolite accumulation pattern of medicinal materials at different harvest periods of Astragalus membranaceus mongholicus, BMC Plant Biology, 24: 5030. https://doi.org/10.1186/s12870-024-05030-7 Liang J., Li W., Jia X., Zhang Y., and Zhao J., 2020, Transcriptome sequencing and characterization of Astragalus membranaceus var. mongholicus root reveals key genes involved in flavonoids biosynthesis, Genes & Genomics, 42(8): 901-914. https://doi.org/10.1007/s13258-020-00953-5 Liu D., Zhang Y., Fan G., Sun D., Zhang X., Yu Z., Wang J., Wu L., Shi W., and Jiang J., 2022, IPGA: a handy integrated prokaryotes genome and pan-genome analysis web service, iMeta, 1: e55. https://doi.org/10.1002/imt2.55 Liu Y., Chen Y., and Fu X., 2020, The complete chloroplast genome sequence of medicinal plant: Astragalus laxmannii (Fabaceae), Mitochondrial DNA Part B, 5(3): 3643-3644 https://doi.org/10.1080/23802359.2020.1829122 Liu Y., Wang X., Zhang M., Li F., Wang Y., Feng Y., Yu H., Gu Y., Liu J., and Gao W., 2025, Integrated assessment of phenotypic traits and bioactive compounds in Astragalus membranaceus var. mongholicus, Horticulturae, 11(3): 317. https://doi.org/10.3390/horticulturae11030317 Liu Y., Zhang P., Zhang R., Song M., Liu F., Wang W., and Hou J., 2016, Analysis on genetic diversity of Radix Astragali by ISSR markers, Advances in Bioscience and Biotechnology, 7(10): 381-391. https://doi.org/10.4236/abb.2016.710037

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