Medicinal Plant Research 2024, Vol.14, No.5, 297-307 http://hortherbpublisher.com/index.php/mpr 305 The findings from these studies suggest several avenues for future research and practical applications in the G. lucidumcultivation industry. Future research should focus on optimizing substrate formulations to maximize yield and bioactive compound content. This includes exploring the effects of different substrate combinations and enrichment with chemical supplements, such as manganese sulfate and nano manganese oxide, which have been shown to enhance yield and ganoderic acid content. Additionally, the impact of environmental conditions, such as temperature and humidity, on the cultivation process should be further investigated to develop standardized protocols for different substrates. For industry adoption, it is recommended to utilize locally available agro-wastes and wood residues as substrates to reduce costs and promote sustainability. Substrates like wheat straw, coconut wood log sawdust, and pecan wood chips have demonstrated high potential and should be considered for large-scale cultivation. Moreover, the incorporation of cold treatments and substrate enrichment strategies can further enhance the yield and quality of G. lucidumfruiting bodies, making the cultivation process more efficient and economically viable. The cultivation of G. lucidumon various substrates offers a sustainable and cost-effective approach to producing this valuable medicinal mushroom. The study highlights the importance of substrate selection and optimization in achieving high yields and enhancing the bioactive properties of the fruiting bodies. By leveraging locally available agro-wastes and wood residues, the G. lucidumcultivation industry can not only improve its economic efficiency but also contribute to environmental sustainability. Future research and industry practices should continue to focus on optimizing substrate formulations and cultivation conditions to fully realize the potential of G. lucidum cultivation. Acknowledgments The author sincerely thanks Ms. Li from the Medicinal Plant Research Center for her invaluable assistance in data analysis and organization. Heartfelt appreciation is also extended to the two anonymous peer reviewers for their meticulous review, which improved the manuscript. Conflict of Interest Disclosure The author affirms that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. Reference Ahmad M.F., Ahmad F.A., Khan M.I., Alsayegh A.A., Wahab S., Alam M.I., and Ahmed F., 2021, Ganoderma lucidum: A potential source to surmount viral infections through β-glucans immunomodulatory and triterpenoids antiviral properties, International Journal of Biological Macromolecules, 187: 769-779. https://doi.org/10.1016/j.ijbiomac.2021.06.122 Amiri-Sadeghan A., Aftabi Y., Arvanaghi H.R., Shokri E., Khalili M., Seyedrezazadeh E., and Kuhar F., 2022, A review of substrates for solid-state fermentation of lingzhi or reishi medicinal mushroom, Ganoderma lucidum (Agaricomycetes), for basidiome production and effect on bioactive compounds, International Journal of Medicinal Mushrooms, 24(4): 15-29. https://doi.org/10.1615/intjmedmushrooms.2022043192 Atila F., 2020, Comparative study on the mycelial growth and yield of Ganoderma lucidum (Curt.: Fr.) Karst. on different lignocellulosic wastes, Acta Ecologica Sinica, 40(2): 153-157. https://doi.org/10.1016/J.CHNAES.2018.11.007 Balasubramanian S., and Kannan P., 2023, Growth efficiency of elm oyster mushroom (Hypsizygus ulmarius) using plant-based waste substrates, Recycling and Sustainable Development, 16(1): 29-40. https://doi.org/10.5937/ror2301029b Bidegain M.A., Postemsky P.D., Pieroni O., and Cubitto M.A., 2019, Analysis of the influence of substrate formulations on the bioactive chemical profile of lingzhi or reishi medicinal mushroom, Ganoderma lucidum (Agaricomycetes) by conventional and chemometrics methods, International Journal of Medicinal Mushrooms, 21(6): 537-548. https://doi.org/10.1615/INTJMEDMUSHROOMS.2019030869 Cortina-Escribano M., Pihlava J.M., Miina J., Veteli P., Linnakoski R., and Vanhanen H., 2020, Effect of strain, wood substrate and cold treatment on the yield and β-glucan content of Ganoderma lucidumfruiting bodies, Molecules, 25(20): 4732. https://doi.org/10.3390/molecules25204732 Fedorov V.S., Ryazanova T.V., Litovka Y.A., Pavlov I.N., Litvinova E.A., Petrunina E.A., Loskutov S.R., Ermolin V.N., and Bayandin M.A., 2022, Hydrodynamically Activated Sawdust of Common Pine Pinus sylvestris L.-substrate for Cultivation of the Strain Gl4–16AGanoderma lucidum, Journal of Siberian Federal University. Chemistry, 15(1): 90-101. https://doi.org/10.17516/1998-2836-0274
RkJQdWJsaXNoZXIy MjQ4ODYzNA==