Medicinal Plant Research 2024, Vol.14, No.5, 259-274 http://hortherbpublisher.com/index.php/mpr 271 individuals with metabolic disorders, leveraging its antidiabetic and lipid-regulating effects to manage blood sugar levels and improve metabolic health. The use of advanced delivery systems, such as nanoparticles and liposomes, can further enhance the bioavailability and targeted delivery of Sanghuangporus bioactives, increasing their therapeutic efficacy. In summary, the future of Sanghuangporus research and application holds significant promise. Through continued scientific exploration and innovation, Sanghuangporus can be integrated into modern healthcare as a valuable resource for both preventive and therapeutic strategies, offering new avenues for managing chronic diseases and promoting overall health. 9 Concluding Remarks Sanghuangporus is a medicinal mushroom with a rich history in traditional medicine and an expanding body of scientific evidence supporting its diverse pharmacological effects. This review has highlighted the multifaceted therapeutic properties of Sanghuangporus, including its antioxidant, anti-tumor, anti-inflammatory, immunomodulatory, hepatoprotective, antidiabetic, and cardiovascular protective effects. These effects are largely attributed to the bioactive compounds found in Sanghuangporus, such as polysaccharides, triterpenoids, and flavonoids. Preclinical studies have shown that these compounds can modulate cellular and molecular pathways involved in chronic disease progression, offering a promising natural approach to disease management. However, to fully understand the medicinal value of Sanghuangporus, future research needs to delve deeper into its chemical composition. This involves detailed botanical identification of Sanghuangporus and the use of modern extraction and separation techniques to identify and purify more bioactive compounds. This process requires not only interdisciplinary collaboration but also the application of advanced analytical technologies, such as high-performance liquid chromatography (HPLC), mass spectrometry (MS), and nuclear magnetic resonance (NMR), to ensure the accuracy and comprehensiveness of the research. Sanghuangporus's potential in preventing and treating various chronic diseases is particularly noteworthy. Its antioxidant and anti-inflammatory properties make it a strong candidate for managing oxidative stress-related conditions, such as cardiovascular diseases and neurodegenerative disorders. The antitumor and immunomodulatory effects of Sanghuangporus suggest its possible use as an adjunct therapy in cancer treatment, either to enhance the efficacy of conventional treatments or to mitigate their side effects. Additionally, Sanghuangporus's hepatoprotective and antidiabetic activities highlight its potential role in managing liver diseases and metabolic disorders, providing a natural means to improve liver function and regulate blood glucose levels. Although these findings are encouraging, it remains necessary to develop new, feasible, cost-effective, and efficient strategies, along with establishing corresponding databases, to optimize the cultivation and preparation of each type of Sanghuangporus. This will facilitate standardization, industrialization, and commercialization. While preclinical studies have provided valuable insights into its mechanisms of action and potential therapeutic benefits, more extensive clinical trials are needed to establish its efficacy, safety, and optimal dosing in humans. Addressing the challenges related to standardization and quality control of Sanghuangporus extracts will be crucial for its development into reliable therapeutic agents. In conclusion, Sanghuangporus offers a promising avenue for future therapeutic development. Its broad spectrum of pharmacological activities and low toxicity make it an attractive candidate for integration into modern healthcare as a natural treatment or preventive measure for various chronic diseases. However, there remains a significant amount of research to be conducted onSanghuangporus and its key active component, polysaccharides. As research progresses, Sanghuangporus has the potential to be developed into functional foods, dietary supplements, and novel pharmaceuticals, contributing to a holistic approach to health and wellness. The journey from traditional use to modern therapeutic application underscores the importance of Sanghuangporus in the evolving landscape of natural medicine.
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