Medicinal Plant Research 2024, Vol.14, No.4, 196-209 http://hortherbpublisher.com/index.php/mpr 207 should focus on elucidating the precise mechanisms of action of these compounds, optimizing extraction and purification methods, and conducting clinical trials to validate their efficacy and safety in humans. The integration of loquat bioactive compounds into pharmaceutical and nutraceutical formulations could significantly contribute to the management of chronic diseases and the enhancement of overall health. Continued exploration and utilization of these natural compounds will provide references for innovative and sustainable health solutions. Acknowledgments The author is very grateful to Ms. Wang of the Horticultural Herbal Research Group for her assistance in literature compilation and data analysis. Meanwhile, the author also wishes to express sincere appreciation to the two anonymous peer reviewers for their contributions during the review process of this manuscript. Conflict of Interest Disclosure The author affirms that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References Ahn Y.J., and Kim H., 2021, Lutein as a modulator of oxidative stress-mediated inflammatory diseases, Antioxidants, 10(9): 1448. https://doi.org/10.3390/antiox10091448 Bisso B.N., Kayoka-Kabongo P.N., Tchuenguem R.T., and Dzoyem J.P., 2022, Phytochemical analysis and antifungal potentiating activity of extracts from loquat (Eriobotrya japonica) against Cryptococcus neoformans clinical isolates, Advances in Pharmacological and Pharmaceutical Sciences, 2022: 6626834. https://doi.org/10.1155/2022/6626834 Castillo-Chuquizuta N., Balcázar-Zumaeta C., Ricce-Villanueva M., and Chavez-Quintana S., 2023, Changes in bioactive compounds in fruits of Eriobotrya japonica grown in three different locations in northeastern Peru, Agrociencia. https://doi.org/10.47163/agrociencia.v57i4.2566 Chen J., Ding X., Wu R., Tong B., Zhao L., Lv H., Meng X., Liu Y., Ren B., Li J., Jian T., and Li W., 2021, Novel sesquiterpene glycoside from loquat leaf alleviates type 2 diabetes mellitus combined with nonalcoholic fatty liver disease by improving insulin resistance, oxidative stress, inflammation, and gut microbiota composition, Journal of Agricultural and Food Chemistry, 69(47): 14176-14191. https://doi.org/10.1021/acs.jafc.1c05596 Chen S.Y., Huang P.H., Shih M.K., Wu C.C., Hsieh C.W., Chen M.H., Hsieh S., and Hou C.Y., 2023, Functional evaluation of loquat (Eriobotrya japonica Lindl.) flower water extracts and its potential use in tea, Journal of Food Processing and Preservation, 2023: 1188178. https://doi.org/10.1155/2023/1188178 Dehelean C.A., Marcovici I., Şoica C., Mioc M., Coricovac D., Iurciuc S., Crețu O., and Pinzaru I., 2021, Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy, Molecules, 26(4): 1109. https://doi.org/10.3390/molecules26041109 Deng H., Li X., Wang Y., Ma Q., Zeng Y., Xiang Y., Chen M., Zhang H., Xia H., Liang D., Lv X., Wang J., and Deng Q., 2023, Organic acid accumulation and associated dynamic changes in enzyme activity and gene expression during fruit development and ripening of common loquat and its interspecific hybrid, Foods, 12(5): 911. https://doi.org/10.3390/foods12050911 Dhiman A., Suhag R., Thakur D., Gupta V., and Prabhakar P.K., 2022, Current status of loquat (Eriobotrya japonica Lindl.): Bioactive functions, preservation approaches, and processed products, Food Reviews International, 38(sup1): 286-316. https://doi.org/10.1080/87559129.2020.1866007 de Almeida Lopes M.M., Sanches A.G., de Souza K.O., and de Oliveira Silva E., 2018, Loquat/Nispero-Eriobotrya japonica Lindl., Exotic Fruits, pp. 285-292. https://doi.org/10.1016/B978-0-12-803138-4.00037-X Fu Y., Feng K.L., Wei S.Y., Xiang X.R., Ding Y., Li H.Y., Zhao L., Qin W., Gan R., and Wu D.T., 2019, Comparison of structural characteristics and bioactivities of polysaccharides from loquat leaves prepared by different drying techniques, International Journal of Biological Macromolecules, 145: 611-619. https://doi.org/10.1016/j.ijbiomac.2019.12.226 Fu Y., Li F., Ding Y., Li H., Xiang X., Ye Q., Zhang J., Zhao L., Qin W., Gan R., and Wu D., 2020, Polysaccharides from loquat (Eriobotrya japonica) leaves: Impacts of extraction methods on their physicochemical characteristics and biological activities, International Journal of Biological Macromolecules, 146: 508-517. https://doi.org/10.1016/j.ijbiomac.2019.12.273 Giordano R., Saii Z., Fredsgaard M., Hulkko L.S., Poulsen T.B.G., Thomsen M.E., Henneberg N., Zucolotto S., Arendt-Nielsen L., Papenbrock J., Thomsen M., and Stensballe A., 2021, Pharmacological insights into halophyte bioactive extract action on anti-inflammatory, pain relief and antibiotics-type mechanisms, Molecules, 26(11): 3140. https://doi.org/10.3390/molecules26113140
RkJQdWJsaXNoZXIy MjQ4ODYzNA==