Medicinal Plant Research 2024, Vol.14, No.4, 196-209 http://hortherbpublisher.com/index.php/mpr 204 Figure 4 Effects of SG3 (25 and 50 mg/kg/day) on liver pathological changes and serum steatosis metabolism in diabetic db/db mice; 150 mg/kg of Met was used as a positive control (Adopted from Chen et al., 2021) Image caption: Figure A shows the appearance of mouse liver, H&E staining, and Oil Red O staining results, indicating that SG3 treatment significantly reduced liver steatosis and inflammatory cell infiltration, thereby improving liver tissue structure. Figures B-E demonstrate the effects of SG3 on serum total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) levels, showing that SG3 lowered TC, TG, and LDL levels while increasing HDL levels. These results confirm the efficacy of SG3 in alleviating fatty liver and regulating lipid metabolism, supporting its potential as a therapeutic approach for diabetes-related NAFLD (Adapted from Chen et al., 2021)
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