Medicinal Plant Research 2024, Vol.14, No.3, 126-136 http://hortherbpublisher.com/index.php/mpr 126 Feature Review Open Access Medical Wonders of Chrysanthemum morifolium: Fusion of Traditional Chinese Medicine and Modern Science Lanjie Xu, Yongliang Yu, Zhengwei Tan, Chunming Li, Qing Yang, Hongqi Yang, Xiaoyu Su, Yao Sun, Huizhen Liang Institute of Chinese Herbal Medicine, He'nan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, China Corresponding author: lhzh66666@163.com Medicinal Plant Research, 2024, Vol.14, No.3 doi: 10.5376/mpr.2024.14.0011 Received: 27 Mar., 2024 Accepted: 29 Apr., 2024 Published: 10 May, 2024 Copyright © 2024 Xu et al., This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Preferred citation for this article: Xu L.J., Yu Y.L., Tan Z.W., Li C.M., Yang Q., Yang H.Q., Su X.Y., Sun Y., and Liang H.Z., 2024, Medical wonders of Chrysanthemum morifolium: fusion of traditional Chinese medicine and modern science, Medicinal Plant Research, 14(3): 126-136 (doi: 10.5376/mpr.2024.14.0011) Abstract Chrysanthemum is an important component of traditional Chinese medicine (TCM), has been highly praised for its special therapeutic effects for over 2000 years. This study integrate the research results of traditional and modern medicinal effects of chrysanthemum, in order to broaden its application prospects and develop new drugs, health products, etc. The active ingredients of chrysanthemum, such as naringenin and apigenin, have shown antidepressant effects by regulating various metabolic pathways such as tryptophan and phenylalanine metabolism; The synergistic effect of active ingredients such as apigenin and kaempferol in chrysanthemum has the effect of treating diseases such as gout by inhibiting the activity of xanthine oxidase. Chrysanthemum extract exhibits strong antibacterial properties against Streptococcus mutans and other bacteria, and is expected to become a candidate drug for the treatment of postoperative sore throat. Ethnic pharmacology research emphasizes that chrysanthemum extract has multiple pharmacological activities, including anti-inflammatory, antioxidant, and therapeutic effects on cardiovascular diseases. Combining traditional uses with modern medical research achievements, exploring the potential of chrysanthemum as a modern medical raw material. Keywords Chrysanthemum morifolium; Traditional Chinese medicine; Biological activity; Extractive; Clinical application 1 Introduction Chrysanthemum morifoliumis a flower and medicinal plant with a long history of cultivation and medicinal use (Lee et al., 2021). Chrysanthemum revered in Traditional Chinese medicine (TCM) for thousands of years, this herb has been utilized for its remarkable therapeutic properties, chrysanthemum has a wide range of disease treatments, including inflammation, eye diseases, immunity, etc. It is a treasure gifted to humans by nature. The chrysanthemum's medicinal lore is steeped in ancient texts and traditional practices, symbolizing a bridge between nature's bounty and human health. In recent years, the close combination of modern medical technology and traditional Chinese herbal medicine further reveals the credibility of chrysanthemum medicine, that hold promise for contemporary medicine. The combination of traditional Chinese medicine decoctions and modern medical research results has prompted people to have a new understanding of the therapeutic potential of chrysanthemum. This not only proves the efficacy of traditional Chinese medicine decoctions, but also discovers new therapeutic effects, which may have a revolutionary turning point for the treatment of diseases in traditional Chinese medicine (Chen et al., 2020; Wang et al., 2022). This study aims to comprehensively study the pharmacological properties of chrysanthemums and their therapeutic potential, combining traditional uses with modern scientific discoveries. Research results on active ingredients such as flavonoids, phenolic acids, and essential oils in chrysanthemum, as well as mechanisms of related pharmacological and pharmacological activities. In particular, the focus is on the integration of traditional applications within the framework of contemporary clinical research, highlighting the advantages and characteristics of traditional Chinese medicine combined with modern science and technology, guiding the research, development, production, management, and application of traditional Chinese medicine to meet the
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