MPR_2024v14n1

Medicinal Plant Research 2024, Vol.14, No.1, 45-56 http://hortherbpublisher.com/index.php/mpr 54 times, and implementing sustainable pest management strategies. Additionally, understanding the relationship between cultivation conditions and the chemical composition of C. morifoliumcan help in producing high-quality plants with consistent bioactive profiles (Chen et al., 2020). By addressing these future directions and research opportunities, we can unlock the full potential of Chrysanthemum morifoliumand enhance its applications in various fields, from medicine to food science. 9 Concluding Remarks The comprehensive study on the chemical characteristics and bioactivity of Chrysanthemum morifolium has revealed several significant findings. The essential oils of C. morifoliumcontain a variety of bioactive compounds, with camphor being a major constituent, which contributes to its notable antimicrobial and antioxidant activities. The flower extract of C. morifolium has shown potential in ameliorating obesity-induced inflammation and enhancing muscle mitochondrial content and AMPK/SIRT1 activities in obese rats, indicating its role in metabolic health. Additionally, C. morifoliumis rich in flavonoids and caffeoylquinic acids, which are associated with its antioxidant properties and potential use as a natural preservative. The flower extract also exhibits significant anti-inflammatory and free radical scavenging activities, which can modulate gut microbiota and improve overall health. Furthermore, the neuroprotective effects of certain compounds isolated fromC. morifoliumhighlight its potential in treating neurodegenerative diseases. The extract has also demonstrated efficacy in reducing lipid and protein oxidation in meat products, suggesting its application as a natural antioxidant in the food industry. The findings from this study open several avenues for future research. Firstly, further investigation into the specific mechanisms underlying the bioactive effects of C. morifolium, particularly its anti-inflammatory and antioxidant properties, is warranted. This could involve exploring the molecular pathways and identifying additional bioactive compounds responsible for these effects. Secondly, the potential of C. morifoliumin treating metabolic disorders, such as obesity and hyperuricemia, should be explored in more detail, including clinical trials to validate its efficacy and safety in humans. Additionally, the neuroprotective properties of C. morifoliumwarrant further research to develop potential therapeutic agents for neurodegenerative diseases. Lastly, the application of C. morifolium as a natural preservative in the food industry should be expanded, with studies focusing on its effectiveness in various food products and its impact on sensory qualities. In conclusion, Chrysanthemum morifolium exhibits a wide range of bioactivities, including antimicrobial, antioxidant, anti-inflammatory, and neuroprotective effects. These properties make it a promising candidate for various applications in the fields of medicine, food preservation, and functional foods. The rich chemical composition of C. morifolium, particularly its flavonoids and caffeoylquinic acids, underpins its health benefits and potential therapeutic uses. Future research should aim to further elucidate the mechanisms of action, optimize extraction methods, and conduct clinical trials to fully harness the potential of this versatile plant. The integration of C. morifolium into health-promoting products could significantly contribute to improving public health and well-being. Conflict of Interest Disclosure The authors affirm that this research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. References Cai Y., Gao Y., Zhang Z., Liu H., Wang Y., Ma Y., Li Y., Feng S., and Wang H., 2022, Development and application of a cultivar-specific sequence-characterized amplified region (SCAR) marker for the detection of Chrysanthemum morifoliumRamat. ‘Daboju’, Plants, 11(5):604. https://doi.org/10.3390/plants11050604 PMid:35270074 PMCid:PMC8912837 Chen S., Liu J., Dong G., Zhang X., Liu Y., Sun W., and Liu A., 2020, Flavonoids and caffeoylquinic acids in Chrysanthemum morifoliumRamat flowers: A potentially rich source of bioactive compounds, Food Chemistry, 344: 128733. https://doi.org/10.1016/j.foodchem.2020.128733 PMid:33280963

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