Medicinal Plant Research 2024, Vol.14, No.1, 11-30 http://hortherbpublisher.com/index.php/mpr 25 Further research is needed to isolate and identify more active compounds from aromatic medicinal plants and to establish the links between these compounds and their pharmacological activities (Saleh-E-In and Choi, 2021; Mesmar et al., 2022). Studies focusing on the structure-activity relationship and in vivo mechanistic studies are particularly important to validate the therapeutic potential of these plants (Ebrahimi et al., 2020; Saleh-E-In and Choi, 2021). Moreover, there is a need for pharmacokinetic evaluation tests to validate the bioavailability and safety of these compounds. To address these gaps, a multidisciplinary approach involving ethnobotany, pharmacology, and advanced analytical techniques should be employed. Collaborative efforts between researchers and traditional medicine practitioners can provide valuable insights into the traditional uses of these plants and guide pharmacological studies (Saleh-E-In and Choi, 2021; Šarčević-Todosijević et al., 2023). Additionally, the use of advanced technologies such as omics techniques can help in understanding the complex interactions between the bioactive compounds and their targets (Christaki et al., 2020). 9.2 Technological and methodological advances Recent innovations in research methodologies, such as the development of robust LC-MS/MS methods, have significantly improved the screening and quantification of phytochemicals in medicinal and aromatic plants (Yılmaz et al., 2020). These advancements allow for more accurate and comprehensive analysis of plant extracts, facilitating the identification of bioactive compounds and their pharmacological properties (Yılmaz et al., 2020). The use of advanced analytical techniques, including liquid chromatography-tandem mass spectrometry (LC-MS/MS) and other high-throughput screening methods, has enhanced the reliability and reproducibility of phytochemical analysis (Yılmaz et al., 2020). These techniques enable the detailed characterization of complex plant extracts and the identification of novel bioactive compounds with potential therapeutic applications (Petrović et al., 2019; Yılmaz et al., 2020). The integration of these technological and methodological advances into pharmacological research can lead to the discovery of new drug leads and the development of more effective and safer therapeutic agents derived from aromatic medicinal plants. These advancements also provide a better understanding of the mechanisms of action of these compounds, which is crucial for their clinical application (Petrović et al., 2019; Yılmaz et al., 2020). 9.3 Policy and funding considerations Policy decisions play a crucial role in shaping the research and development landscape for aromatic medicinal plants. Supportive policies that promote the conservation and sustainable use of these plants can enhance research efforts and ensure the availability of plant resources for future studies (Ebrahimi et al., 2020; Šarčević-Todosijević et al., 2023). Additionally, policies that encourage collaboration between academic institutions, industry, and traditional medicine practitioners can facilitate the translation of research findings into practical applications (Šarčević-Todosijević et al., 2023). Securing funding for research on aromatic medicinal plants remains a significant challenge. While there are funding opportunities available from government agencies, non-profit organizations, and industry, competition for these funds is often intense (Ebrahimi et al., 2020; Šarčević-Todosijević et al., 2023). Moreover, the interdisciplinary nature of this research requires substantial investment in advanced technologies and collaborative efforts, which can be financially demanding. To support the advancement of research on aromatic medicinal plants, it is essential to advocate for increased funding and policy support. This includes promoting the importance of this research to policymakers and funding agencies, highlighting its potential to contribute to drug discovery and public health. Additionally, establishing dedicated funding programs and research centers focused on medicinal plant research can provide the necessary resources and infrastructure to drive innovation in this field.
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