MPR_2024v14n1

Medicinal Plant Research 2024, Vol.14, No.1, 11-30 http://hortherbpublisher.com/index.php/mpr 23 may indeed have enhanced therapeutic effects. Furthermore, the study emphasizes the need for pharmacological research into herbal interactions to ensure their efficacy and safety. This finding provides scientific evidence for the application of herbs in pain treatment, supporting their potential in both traditional and modern medicine. Figure 2 BALB/c peritoneal macrophages infected with Trypanosoma cruzi and treated with Syzygium aromaticumessential oil or eugenol for 24 hours (Adopted from Teles et al., 2021) Image caption: The figure shows the infection parameters of BALB/c peritoneal macrophages infected with Trypanosoma cruzi after treatment with different concentrations of clove (Syzygium aromaticum) essential oil and eugenol. Figure 2(a) demonstrates that essential oil at concentrations of 200 µg/mL and 100 µg/mL significantly reduced the number of amastigotes (A non-flagellated form of Trypanosoma cruzi) per 100 cells (p < 0.0068 and p < 0.0460, respectively). Figures 2(b) and 2(d) indicate that 200 µg/mL of eugenol also significantly reduced the number of amastigotes per 100 cells (p < 0.0095) and the number of amastigotes per infected cell (p < 0.0112). The microscopic images Figure 2(e) show a reduction in the intracellular amastigotes after treatment. These results suggest that clove essential oil and eugenol have significant potential as anti-trypanosomal agents (Adapted from Teles et al., 2021)

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