MPR_2024v14n1

Medicinal Plant Research 2024, Vol.14, No.1, 11-30 http://hortherbpublisher.com/index.php/mpr 19 Samarth et al., 2017; Kieliszek et al., 2020). For instance, essential oils from plants like myrrh (Commiphora myrrha (Nees) Engl.), ginger (Zingiber officinale), and turmeric (Curcuma longa) have shown promising biological activities that can protect against or alleviate various ailments (Kieliszek et al., 2020; Zhang et al., 2023). Additionally, clove (Syzygium aromaticum) has been used for its analgesic, antioxidant, anticancer, antiseptic, antidepressant, antispasmodic, anti-inflammatory, antiviral, antifungal, and antibacterial properties (Batiha et al., 2020). Several clinical trials and case studies have been conducted to evaluate the effectiveness of aromatic medicinal plants. For example, essential oils and extracts from Greek aromatic plants have been studied for their antiproliferative potential against different types of cancer, showing promising results in inhibiting cancer cell growth (Fitsiou and Pappa, 2019). Similarly, the radioprotective activity of certain aromatic plants has been documented, highlighting their potential in protecting against radiation-induced damage (Samarth et al., 2017). Moreover, the use of essential oils and volatile compounds in Alzheimer's disease therapy has been explored, with some studies suggesting their potential in improving cognitive functions (Maggio et al., 2016). The effectiveness of aromatic medicinal plants in clinical settings has been supported by various studies. For instance, plant-derived compounds that modulate oxidative stress have shown potential in cancer therapeutics by inducing cytotoxicity and apoptosis in cancer cells (Vallejo et al., 2017). Additionally, the integration of these plants into the diet has been encouraged to boost overall health, supported by scientific evidence (Kieliszek et al., 2020). Patient outcomes have generally been positive, with many studies reporting significant improvements in symptoms and overall health status (Fitsiou and Pappa, 2019; Kieliszek et al., 2020; Batiha et al., 2020). 6.2 Potential for new therapies Emerging research continues to explore the therapeutic potential of aromatic medicinal plants. Recent studies have focused on the bioactive compounds in these plants and their mechanisms of action, which could lead to the development of new therapies (Vallejo et al., 2017; Krishnaprabu et al., 2020). For example, the antioxidant and anti-inflammatory properties of polyphenols in medicinal plants are being investigated for their potential health benefits (Šarčević-Todosijević et al., 2023). Additionally, the discovery of new bioactive molecules through phytochemical screening has opened up possibilities for novel drug development (Krishnaprabu et al., 2020). Aromatic medicinal plants hold potential for new therapeutic areas beyond their traditional uses. For instance, their radioprotective properties could be harnessed in cancer treatment to protect healthy cells from radiation damage (Samarth et al., 2017). Furthermore, the neuroprotective effects of essential oils and volatile compounds are being explored for the treatment of neurodegenerative diseases like Alzheimer's (Maggio et al., 2016). The antimicrobial and antiviral properties of these plants also present opportunities for developing new treatments for infectious diseases (Batiha et al., 2020). While the therapeutic potential of aromatic medicinal plants is promising, there are several challenges in developing new therapies. One major challenge is the need for more clinical trials to establish the efficacy and safety of these plants in routine healthcare (Maggio et al., 2016). Additionally, the variability in the chemical composition of plant extracts can affect their pharmacological activity, necessitating standardization and quality control (Fitsiou and Pappa, 2019). However, these challenges also present opportunities for further research and innovation in the field of natural product-based drug development (Krishnaprabu et al., 2020; Šarčević-Todosijević et al., 2023). 6.3 Integration into conventional medicine The integration of aromatic medicinal plants with conventional treatments is an area of growing interest. These plants can serve as adjuvants to enhance the efficacy of synthetic drugs or reduce their side effects (Kieliszek et al., 2020). For example, combining plant-derived antioxidants with conventional cancer therapies could improve treatment outcomes by protecting healthy cells from oxidative damage (Vallejo et al., 2017). Additionally, the use of essential oils in aromatherapy has been shown to complement conventional treatments for various conditions, including stress and anxiety (Maggio et al., 2016).

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