6 - IJMZ-Vol.3-No.5页
基本HTML版本
Int
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l J. Mol. Zoo., 2013, Vol.3, No.5, 17
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19
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of the antidepressant drugs, the treatment of depressive
illness maybe achieved by inhibiting the activity.
Cytochrome P450 super family
is considered
to encode
some
enzymes related to drug metabolism
,
activation
and interaction.
Treeshrew
has very close gene structure
and consistency of cytochrome P450 super family to
human
,
these conservation of the drug targets, together
with the conserved signalling pathways in treeshrews and
humans,
allows the treeshrews
for
evaluating the
studies of drug distribution
,
drug targets
,
pharmacokinetics,
and adverse drug reactions.
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